Dcu_g19678 (MSH6-1, ATMSH6, MSH6)

Aliases : MSH6-1, ATMSH6, MSH6

Description : component *(MSH6) of MSH2-x mismatch repair heterodimers & original description: none

Gene families : OG0001663 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0001663_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Dcu_g19678
Cluster	HCCA: Cluster_176

Target	Alias	Description	ECC score	Gene Family Method	Actions
Lfl_g09319	MSH7, ATMSH7, MSH6-2	component *(MSH7) of MSH2-x mismatch repair heterodimers...	0.03	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000012	single strand break repair	IEP	HCCA
MF	GO:0003684	damaged DNA binding	IEP	HCCA
MF	GO:0003700	DNA-binding transcription factor activity	IEP	HCCA
MF	GO:0004518	nuclease activity	IEP	HCCA
MF	GO:0004519	endonuclease activity	IEP	HCCA
MF	GO:0004521	endoribonuclease activity	IEP	HCCA
MF	GO:0004525	ribonuclease III activity	IEP	HCCA
MF	GO:0004540	ribonuclease activity	IEP	HCCA
CC	GO:0005634	nucleus	IEP	HCCA
BP	GO:0006396	RNA processing	IEP	HCCA
BP	GO:0016070	RNA metabolic process	IEP	HCCA
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	HCCA
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEP	HCCA
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	HCCA
MF	GO:0030246	carbohydrate binding	IEP	HCCA
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	HCCA
CC	GO:0043227	membrane-bounded organelle	IEP	HCCA
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	HCCA
MF	GO:0043565	sequence-specific DNA binding	IEP	HCCA
MF	GO:0140098	catalytic activity, acting on RNA	IEP	HCCA
MF	GO:0140110	transcription regulator activity	IEP	HCCA
MF	GO:0140640	catalytic activity, acting on a nucleic acid	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR007695	DNA_mismatch_repair_MutS-lik_N	363	474
IPR007861	DNA_mismatch_repair_MutS_clamp	889	971
IPR007860	DNA_mmatch_repair_MutS_con_dom	486	647
IPR000432	DNA_mismatch_repair_MutS_C	1086	1277
IPR007696	DNA_mismatch_repair_MutS_core	704	1021

External Links

No external refs found!

Dcu_g19678 (MSH6-1, ATMSH6, MSH6)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation