GO:0016829: lyase activity (Molecular function)

"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [ISBN:0198547684]


There are 2165 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_339 Amborella trichopoda 50.0 % 0.011827 0.023655
Cluster_353 Amborella trichopoda 50.0 % 0.011827 0.032103
Cluster_385 Amborella trichopoda 50.0 % 0.011827 0.023655
Cluster_47 Amborella trichopoda 3.7 % 0.000424 0.007936
Cluster_68 Amborella trichopoda 13.33 % 0.0 0.0
Cluster_272 Amborella trichopoda 25.0 % 0.023516 0.048992
Cluster_77 Amborella trichopoda 10.42 % 1e-05 0.000175
Cluster_88 Amborella trichopoda 4.42 % 0.000578 0.007775
Cluster_112 Amborella trichopoda 6.9 % 0.000394 0.039033
Cluster_14 Arabidopsis thaliana 4.32 % 0.002781 0.030139
Cluster_142 Arabidopsis thaliana 9.3 % 0.000882 0.003645
Cluster_141 Arabidopsis thaliana 9.09 % 1.2e-05 0.000134
Cluster_37 Arabidopsis thaliana 6.15 % 0.004078 0.015525
Cluster_62 Arabidopsis thaliana 5.77 % 0.000627 0.004322
Cluster_395 Arabidopsis thaliana 100.0 % 1e-06 3e-06
Cluster_113 Arabidopsis thaliana 9.47 % 0.0 6e-06
Cluster_171 Chlamydomonas reinhardtii 12.24 % 6e-06 5.1e-05
Cluster_132 Chlamydomonas reinhardtii 7.04 % 0.000534 0.005838
Cluster_167 Chlamydomonas reinhardtii 5.45 % 0.014791 0.027155
Cluster_211 Chlamydomonas reinhardtii 50.0 % 0.018627 0.033966
Cluster_44 Chlamydomonas reinhardtii 10.24 % 0.0 0.0
Cluster_58 Chlamydomonas reinhardtii 9.35 % 0.0 0.0
Cluster_53 Chlamydomonas reinhardtii 5.41 % 7.7e-05 0.00031
Cluster_61 Chlamydomonas reinhardtii 8.2 % 0.000263 0.019866
Cluster_34 Chlamydomonas reinhardtii 4.14 % 0.001073 0.005189
Cluster_95 Chlamydomonas reinhardtii 7.0 % 4.3e-05 0.000151
Cluster_72 Chlamydomonas reinhardtii 6.9 % 0.002117 0.008469
Cluster_76 Cyanophora paradoxa 3.67 % 0.005212 0.020568
Cluster_166 Cyanophora paradoxa 2.72 % 0.006514 0.039543
Cluster_86 Cyanophora paradoxa 3.73 % 0.000587 0.017423
Cluster_135 Cyanophora paradoxa 6.56 % 0.000618 0.014593
Cluster_87 Cyanophora paradoxa 5.26 % 0.001412 0.013181
Cluster_152 Cyanophora paradoxa 7.14 % 0.002411 0.041791
Cluster_55 Cyanophora paradoxa 4.42 % 2.1e-05 0.000438
Cluster_18 Cyanophora paradoxa 4.07 % 0.001151 0.018249
Cluster_295 Gingko biloba 7.69 % 0.000103 0.002345
Cluster_134 Gingko biloba 3.95 % 0.005418 0.04334
Cluster_604 Gingko biloba 33.33 % 0.013879 0.038168
Cluster_3 Gingko biloba 3.55 % 0.000534 0.006763
Cluster_180 Gingko biloba 7.25 % 0.0 0.0
Cluster_19 Gingko biloba 4.9 % 0.000119 0.003656
Cluster_207 Gingko biloba 3.8 % 0.006033 0.027842
Cluster_364 Gingko biloba 50.0 % 0.009274 0.020656
Cluster_64 Gingko biloba 2.39 % 0.003038 0.022091
Cluster_594 Gingko biloba 50.0 % 0.009274 0.020404
Cluster_331 Marchantia polymorpha 50.0 % 0.00935 0.024932
Cluster_35 Marchantia polymorpha 3.45 % 0.007943 0.026274
Cluster_110 Marchantia polymorpha 3.61 % 0.006978 0.031403
Cluster_11 Marchantia polymorpha 2.75 % 0.014617 0.034025
Cluster_123 Marchantia polymorpha 2.27 % 0.009453 0.029438
Cluster_41 Marchantia polymorpha 7.41 % 0.000119 0.002703
Cluster_70 Oryza sativa 2.0 % 0.013017 0.038407
Cluster_337 Oryza sativa 3.85 % 0.005339 0.025388
Cluster_169 Oryza sativa 3.75 % 0.005728 0.03423
Cluster_318 Oryza sativa 3.75 % 0.005728 0.028181
Cluster_26 Oryza sativa 5.0 % 0.002548 0.007433
Cluster_4 Oryza sativa 2.84 % 0.003892 0.030099
Cluster_208 Oryza sativa 4.85 % 0.000108 0.004654
Cluster_365 Oryza sativa 5.77 % 0.001689 0.012548
Cluster_147 Oryza sativa 3.57 % 0.006556 0.032185
Cluster_65 Oryza sativa 4.44 % 0.000753 0.001032
Cluster_96 Oryza sativa 3.2 % 0.002527 0.016507
Cluster_172 Physcomitrella patens 2.78 % 0.001895 0.011161
Cluster_95 Physcomitrella patens 2.35 % 0.002628 0.02155
Cluster_136 Physcomitrella patens 2.94 % 0.001693 0.007429
Cluster_459 Picea abies 4.76 % 0.000516 0.00753
Cluster_79 Picea abies 5.88 % 3.7e-05 0.00096
Cluster_264 Picea abies 2.91 % 0.000308 0.006643
Cluster_327 Picea abies 7.5 % 1e-06 3.2e-05
Cluster_458 Picea abies 7.94 % 9e-06 0.000285
Cluster_107 Picea abies 11.24 % 0.0 0.0
Cluster_177 Picea abies 5.66 % 0.001627 0.00751
Cluster_1323 Picea abies 50.0 % 0.008686 0.019108
Cluster_857 Picea abies 33.33 % 0.013 0.030334
Cluster_239 Picea abies 5.97 % 0.000217 0.003607
Cluster_571 Picea abies 50.0 % 0.008686 0.026057
Cluster_1021 Picea abies 50.0 % 0.008686 0.020846
Cluster_298 Picea abies 2.06 % 0.010549 0.024502
Cluster_241 Picea abies 3.66 % 0.005608 0.025858
Cluster_172 Picea abies 5.08 % 1.4e-05 0.000297
Cluster_3 Picea abies 2.18 % 0.001383 0.026129
Cluster_449 Picea abies 6.45 % 0.000161 0.003729
Cluster_63 Picea abies 2.17 % 0.008813 0.036695
Cluster_934 Picea abies 50.0 % 0.008686 0.013029
Cluster_614 Picea abies 50.0 % 0.008686 0.033295
Cluster_1304 Picea abies 50.0 % 0.008686 0.013029
Cluster_127 Picea abies 4.41 % 0.003318 0.012468
Cluster_1354 Picea abies 50.0 % 0.008686 0.026057
Cluster_30 Picea abies 6.19 % 0.0 0.0
Cluster_9 Selaginella moellendorffii 2.23 % 0.001141 0.012649
Cluster_34 Solanum lycopersicum 2.44 % 0.011373 0.049729
Cluster_204 Solanum lycopersicum 3.7 % 0.009148 0.02295
Cluster_533 Solanum lycopersicum 50.0 % 0.010537 0.023416
Cluster_168 Solanum lycopersicum 9.09 % 8.7e-05 0.002167
Cluster_256 Solanum lycopersicum 3.85 % 0.008251 0.045657
Cluster_11 Solanum lycopersicum 2.99 % 0.00199 0.013157
Cluster_42 Solanum lycopersicum 8.06 % 0.0 0.0
Cluster_542 Solanum lycopersicum 33.33 % 0.015764 0.031529
Cluster_122 Vitis vinifera 6.56 % 0.001618 0.048005
Cluster_55 Vitis vinifera 6.58 % 0.000416 0.003803
Cluster_151 Vitis vinifera 11.3 % 0.0 0.0
Cluster_396 Vitis vinifera 50.0 % 0.016406 0.045115
Cluster_412 Vitis vinifera 50.0 % 0.016406 0.036092
Cluster_422 Vitis vinifera 50.0 % 0.016406 0.036913
Cluster_56 Vitis vinifera 9.26 % 8.2e-05 0.002292
Cluster_179 Vitis vinifera 4.76 % 0.015232 0.03696
Cluster_76 Zea mays 4.76 % 5.3e-05 0.001225
Cluster_122 Zea mays 4.0 % 0.000121 0.001474
Cluster_297 Zea mays 2.88 % 0.007409 0.044726
Cluster_10 Zea mays 2.67 % 0.000233 0.001403
Cluster_53 Zea mays 4.55 % 0.000365 0.003627
Cluster_597 Zea mays 33.33 % 0.011358 0.026502
Cluster_900 Zea mays 50.0 % 0.007586 0.033596
Cluster_832 Zea mays 50.0 % 0.007586 0.02908
Cluster_581 Zea mays 25.0 % 0.015115 0.026582
Cluster_272 Zea mays 6.94 % 8e-06 8.3e-05
Sequences (2165) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms