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GO:0001181: RNA polymerase I general transcription initiation factor activity (Molecular function)

"A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs." [GOC:txnOH-2018, PMID:11500378, PMID:17972917, PMID:25346433, PMID:28340337, PMID:28842442, PMID:31358304]


There are 621 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_187 Abrodictyum obscurum 0.59 % 0.003921 0.043295
Cluster_122 Actinostachys digitata 0.58 % 0.00524 0.022709
Cluster_104 Angiopteris evecta 0.69 % 0.002886 0.014053
Cluster_120 Adiantum latifolium 1.23 % 0.002045 0.00814
Cluster_102 Alsophila latebrosa 1.06 % 0.002924 0.023891
Cluster_53 Amblovenatum opulentum 0.63 % 0.004416 0.047335
Sequences (621) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms