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GO:0001181: RNA polymerase I general transcription initiation factor activity (Molecular function)

"A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs." [GOC:txnOH-2018, PMID:11500378, PMID:17972917, PMID:25346433, PMID:28340337, PMID:28842442, PMID:31358304]


There are 621 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_187 Abrodictyum obscurum 0.57 % 0.004036 0.042785
Cluster_120 Adiantum latifolium 1.15 % 0.002196 0.007828
Cluster_102 Alsophila latebrosa 1.04 % 0.002986 0.027712
Cluster_471 Amblovenatum opulentum 1.79 % 0.001566 0.026624
Cluster_53 Amblovenatum opulentum 0.53 % 0.005225 0.040463
Cluster_104 Angiopteris evecta 0.62 % 0.003207 0.015615
Cluster_523 Davallia denticulata 1.41 % 0.00135 0.02924
Cluster_565 Lindsaea ensifolia 0.88 % 0.001882 0.048471
Cluster_9 Microlepia speluncae 0.4 % 0.005168 0.029976
Cluster_567 Pleocnemia irregularis 0.79 % 0.003771 0.033563
Cluster_475 Pleocnemia irregularis 1.85 % 0.001617 0.040426
Cluster_431 Salvinia molesta 1.82 % 0.001034 0.015603
Cluster_367 Tectaria incisa 1.1 % 0.001954 0.010073
Cluster_447 Diplazium proliferum (Lam.) Kaulf. 1.59 % 0.001355 0.015417
Cluster_589 Pyrrosia piloselloides 1.72 % 0.0009 0.013945
Cluster_427 Ophioglossum reticulatum 1.72 % 0.001271 0.01377
Cluster_466 Stenochlaena palustris 0.79 % 0.002193 0.047147
Cluster_459 Dicranopteris curranii 0.94 % 0.00204 0.027396
Cluster_425 Alsophila spinulosa 2.33 % 0.001203 0.021133
Sequences (621) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms