Cpa|evm.model.tig00001224.8 (ATMSH2, MSH2)

Aliases : ATMSH2, MSH2

Description : DNA damage response.DNA repair mechanisms.mismatch repair (MMR).MSH2-x mismatch repair heterodimers.MSH2 component

Gene families : OG0004193 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0004193_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Cpa\|evm.model.tig00001224.8
Cluster	HCCA: Cluster_19

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00007p00236950	ATMSH2, MSH2,...	DNA damage response.DNA repair mechanisms.mismatch...	0.03	OrthoFinder output from all 47 species
AT3G18524	ATMSH2, MSH2	MUTS homolog 2	0.07	OrthoFinder output from all 47 species
Ceric.01G010000.1	ATMSH2, MSH2,...	component *(MSH2) of MSH2-x mismatch repair heterodimers...	0.01	OrthoFinder output from all 47 species
Cre01.g003463	ATMSH2, MSH2	DNA mismatch repair protein MSH2 OS=Zea mays	0.08	OrthoFinder output from all 47 species
Dac_g10467	ATMSH2, MSH2	component *(MSH2) of MSH2-x mismatch repair heterodimers...	0.02	OrthoFinder output from all 47 species
GSVIVT01008235001	ATMSH2, MSH2	DNA damage response.DNA repair mechanisms.mismatch...	0.01	OrthoFinder output from all 47 species
Gb_33909	ATMSH2, MSH2	component MSH2 of MSH2-x mismatch repair heterodimers	0.02	OrthoFinder output from all 47 species
LOC_Os05g19270.1	ATMSH2, MSH2,...	component MSH2 of MSH2-x mismatch repair heterodimers	0.01	OrthoFinder output from all 47 species
MA_10431416g0010	ATMSH2, MSH2	DNA mismatch repair protein MSH2 OS=Zea mays...	0.03	OrthoFinder output from all 47 species
MA_59360g0010	ATMSH2, MSH2	component MSH2 of MSH2-x mismatch repair heterodimers	0.05	OrthoFinder output from all 47 species
MA_60574g0010	No alias	DNA mismatch repair protein MSH2 OS=Zea mays...	0.02	OrthoFinder output from all 47 species
Mp4g08420.1	ATMSH2, MSH2	component MSH2 of MSH2-x mismatch repair heterodimers	0.11	OrthoFinder output from all 47 species
Solyc06g069230.3.1	ATMSH2, MSH2,...	component MSH2 of MSH2-x mismatch repair heterodimers	0.04	OrthoFinder output from all 47 species
Tin_g38987	ATMSH2, MSH2	component *(MSH2) of MSH2-x mismatch repair heterodimers...	0.02	OrthoFinder output from all 47 species
Zm00001e035455_P001	ATMSH2, MSH2,...	component MSH2 of MSH2-x mismatch repair heterodimers	0.04	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0001882	nucleoside binding	IEP	HCCA
MF	GO:0003824	catalytic activity	IEP	HCCA
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	HCCA
MF	GO:0003896	DNA primase activity	IEP	HCCA
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	HCCA
MF	GO:0003909	DNA ligase activity	IEP	HCCA
MF	GO:0003910	DNA ligase (ATP) activity	IEP	HCCA
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	HCCA
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	HCCA
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	HCCA
BP	GO:0006231	dTMP biosynthetic process	IEP	HCCA
BP	GO:0006260	DNA replication	IEP	HCCA
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	HCCA
BP	GO:0006270	DNA replication initiation	IEP	HCCA
BP	GO:0006275	regulation of DNA replication	IEP	HCCA
BP	GO:0006310	DNA recombination	IEP	HCCA
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	HCCA
BP	GO:0009124	nucleoside monophosphate biosynthetic process	IEP	HCCA
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	IEP	HCCA
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	IEP	HCCA
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	IEP	HCCA
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	IEP	HCCA
BP	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	IEP	HCCA
BP	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	IEP	HCCA
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	IEP	HCCA
BP	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process	IEP	HCCA
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	HCCA
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	HCCA
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	IEP	HCCA
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	IEP	HCCA
BP	GO:0010639	negative regulation of organelle organization	IEP	HCCA
MF	GO:0016740	transferase activity	IEP	HCCA
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	IEP	HCCA
MF	GO:0016779	nucleotidyltransferase activity	IEP	HCCA
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	HCCA
BP	GO:0018130	heterocycle biosynthetic process	IEP	HCCA
BP	GO:0019438	aromatic compound biosynthetic process	IEP	HCCA
BP	GO:0019692	deoxyribose phosphate metabolic process	IEP	HCCA
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	HCCA
BP	GO:0032780	negative regulation of ATP-dependent activity	IEP	HCCA
BP	GO:0033043	regulation of organelle organization	IEP	HCCA
BP	GO:0033044	regulation of chromosome organization	IEP	HCCA
MF	GO:0034061	DNA polymerase activity	IEP	HCCA
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	HCCA
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	HCCA
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	HCCA
CC	GO:0042555	MCM complex	IEP	HCCA
BP	GO:0043086	negative regulation of catalytic activity	IEP	HCCA
BP	GO:0043462	regulation of ATP-dependent activity	IEP	HCCA
BP	GO:0044092	negative regulation of molecular function	IEP	HCCA
BP	GO:0046073	dTMP metabolic process	IEP	HCCA
BP	GO:0046385	deoxyribose phosphate biosynthetic process	IEP	HCCA
BP	GO:0048519	negative regulation of biological process	IEP	HCCA
BP	GO:0048523	negative regulation of cellular process	IEP	HCCA
MF	GO:0050660	flavin adenine dinucleotide binding	IEP	HCCA
BP	GO:0050790	regulation of catalytic activity	IEP	HCCA
MF	GO:0050797	thymidylate synthase (FAD) activity	IEP	HCCA
BP	GO:0051052	regulation of DNA metabolic process	IEP	HCCA
BP	GO:0051095	regulation of helicase activity	IEP	HCCA
BP	GO:0051097	negative regulation of helicase activity	IEP	HCCA
BP	GO:0051128	regulation of cellular component organization	IEP	HCCA
BP	GO:0051129	negative regulation of cellular component organization	IEP	HCCA
BP	GO:0065009	regulation of molecular function	IEP	HCCA
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	HCCA
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	HCCA
MF	GO:0097747	RNA polymerase activity	IEP	HCCA
MF	GO:0140097	catalytic activity, acting on DNA	IEP	HCCA
MF	GO:0140640	catalytic activity, acting on a nucleic acid	IEP	HCCA
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	HCCA
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	HCCA
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	HCCA
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	HCCA
BP	GO:1905774	regulation of DNA helicase activity	IEP	HCCA
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	HCCA
BP	GO:2001251	negative regulation of chromosome organization	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR000432	DNA_mismatch_repair_MutS_C	789	868
IPR000432	DNA_mismatch_repair_MutS_C	701	788
IPR007861	DNA_mismatch_repair_MutS_clamp	508	599
IPR007696	DNA_mismatch_repair_MutS_core	339	642
IPR007860	DNA_mmatch_repair_MutS_con_dom	184	322

External Links

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Cpa|evm.model.tig00001224.8 (ATMSH2, MSH2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation