Description : 27.3.69 RNA.regulation of transcription.SET-domain transcriptional regulator family Encodes a histone 3 lysine 9 specific methyltransferase involved in the maintenance of DNA methylation. SUVH4/KYP is a SU(VAR)3-9 homolog, a SET domain protein. Known SET domain proteins are involved in epigenetic control of gene expression. There are 10 SUVH genes in Arabidopsis and members of this subfamily of the SET proteins have an additional conserved SRA domain. In kyp mutants, there is a loss of CpNpG methylation. The protein was shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the latter two. There is also evidence that KYP/SUVH4 might be involved in the telomerase-independent process known as Alternative Lengthening of Telomeres. SU(VAR)3-9 homolog 4 (SUVH4)

Gene families : OG_01_0000166 (Gene family) Phylogenetic Tree(s): OG0000166_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR network (cutoff 100): GSVIVT01032986001
Cluster HCCA cluster: Cluster_74

Target Alias Description ECC score Gene Family Method Actions
AT2G35160 SUVH5, SGD9 SU(VAR)3-9 homolog 5 0.02 Gene family
AT5G04940 SUVH1 SU(VAR)3-9 homolog 1 0.03 Gene family
LOC_Os05g41172 Os05g0490700 27.3.69 RNA.regulation of transcription.SET-domain... 0.03 Gene family
Zm00001d005650 GRMZM2G300955 No description available 0.02 Gene family
Zm00001d019195 No alias 27.3.69 RNA.regulation of transcription.SET-domain... 0.02 Gene family
Zm00001d038541 GRMZM2G117458 27.3.69 RNA.regulation of transcription.SET-domain... 0.02 Gene family
Zm00001d043135 GRMZM2G139710 27.3.69 RNA.regulation of transcription.SET-domain... 0.02 Gene family

Type GO Term Name Evidence Source
CC GO:0005634 nucleus IEA InterProScan
MF GO:0008270 zinc ion binding IEA InterProScan
MF GO:0018024 histone-lysine N-methyltransferase activity IEA InterProScan
BP GO:0034968 histone lysine methylation IEA InterProScan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001214 SET_dom 537 671
IPR007728 Pre-SET_dom 417 518
IPR003105 SRA_YDG 227 387
No external refs found!