GSVIVT01030405001 (TOP1BETA, TOP1)

Aliases : TOP1BETA, TOP1

Description : Cell cycle.interphase.DNA replication.preinitiation.TOP1 DNA topoisomerase

Gene families : OG0002461 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0002461_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: GSVIVT01030405001

Target	Alias	Description	ECC score	Gene Family Method
Aspi01Gene51541.t1	TOP1BETA, TOP1,...	DNA topoisomerase *(TOP1) & original description: none	0.02	OrthoFinder output from all 47 species
Gb_13084	TOP1BETA, TOP1	DNA topoisomerase (TOP1)	0.04	OrthoFinder output from all 47 species
Msp_g35484	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.03	OrthoFinder output from all 47 species
Ore_g41412	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.04	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003690	double-stranded DNA binding	IEP	HCCA
MF	GO:0003774	cytoskeletal motor activity	IEP	HCCA
MF	GO:0003777	microtubule motor activity	IEP	HCCA
MF	GO:0003905	alkylbase DNA N-glycosylase activity	IEP	HCCA
MF	GO:0004518	nuclease activity	IEP	HCCA
MF	GO:0005515	protein binding	IEP	HCCA
MF	GO:0005524	ATP binding	IEP	HCCA
CC	GO:0005643	nuclear pore	IEP	HCCA
BP	GO:0006281	DNA repair	IEP	HCCA
BP	GO:0006284	base-excision repair	IEP	HCCA
BP	GO:0006298	mismatch repair	IEP	HCCA
BP	GO:0006950	response to stress	IEP	HCCA
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	HCCA
BP	GO:0007017	microtubule-based process	IEP	HCCA
BP	GO:0007018	microtubule-based movement	IEP	HCCA
MF	GO:0008017	microtubule binding	IEP	HCCA
MF	GO:0008092	cytoskeletal protein binding	IEP	HCCA
MF	GO:0008725	DNA-3-methyladenine glycosylase activity	IEP	HCCA
BP	GO:0009892	negative regulation of metabolic process	IEP	HCCA
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	HCCA
BP	GO:0010629	negative regulation of gene expression	IEP	HCCA
MF	GO:0015631	tubulin binding	IEP	HCCA
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEP	HCCA
MF	GO:0019104	DNA N-glycosylase activity	IEP	HCCA
MF	GO:0030983	mismatched DNA binding	IEP	HCCA
BP	GO:0031047	RNA-mediated gene silencing	IEP	HCCA
BP	GO:0033554	cellular response to stress	IEP	HCCA
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	HCCA
MF	GO:0043015	gamma-tubulin binding	IEP	HCCA
MF	GO:0043733	DNA-3-methylbase glycosylase activity	IEP	HCCA
BP	GO:0048519	negative regulation of biological process	IEP	HCCA
BP	GO:0050896	response to stimulus	IEP	HCCA
MF	GO:0051536	iron-sulfur cluster binding	IEP	HCCA
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	HCCA
MF	GO:0051540	metal cluster binding	IEP	HCCA
BP	GO:0051716	cellular response to stimulus	IEP	HCCA
MF	GO:0140657	ATP-dependent activity	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR013500	TopoI_cat_euk	395	620
IPR008336	TopoI_DNA-bd_euk	181	392
IPR025834	TopoI_C_dom	656	724

External Links

No external refs found!

GSVIVT01030405001 (TOP1BETA, TOP1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation