GO:0003905: alkylbase DNA N-glycosylase activity (Molecular function)

"Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site." [EC:3.2.2.21, GOC:elh, PMID:10872450, PMID:9224623]


There are 2366 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_230 Amborella trichopoda 1.43 % 0.010213 0.042331
Cluster_213 Gingko biloba 1.12 % 0.00859 0.034806
Cluster_273 Oryza sativa 1.14 % 0.014511 0.047606
Cluster_285 Oryza sativa 1.41 % 0.011722 0.04607
Cluster_150 Solanum lycopersicum 1.82 % 0.000366 0.014725
Cluster_355 Zea mays 4.35 % 5.4e-05 0.001704
Cluster_207 Zea mays 1.94 % 0.00027 0.005379
Cluster_344 Zea mays 2.35 % 0.000184 0.001143
Cluster_533 Picea abies 1.69 % 0.00442 0.038893
Cluster_2 Picea abies 0.54 % 0.01388 0.043989
Cluster_526 Alsophila latebrosa 0.62 % 0.01494 0.045303
Cluster_668 Amblovenatum opulentum 2.13 % 0.002627 0.011823
Cluster_439 Angiopteris evecta 1.67 % 0.004801 0.043213
Cluster_174 Lindsaea ensifolia 1.28 % 0.00648 0.019929
Cluster_38 Microlepia speluncae 1.96 % 0.004161 0.041929
Cluster_403 Nephrolepis biserrata 1.92 % 0.00345 0.028545
Cluster_13 Diplazium proliferum (Lam.) Kaulf. 0.69 % 0.01242 0.026954
Cluster_89 Ophioglossum reticulatum 2.86 % 2.3e-05 0.001018
Cluster_435 Ophioglossum reticulatum 1.61 % 0.006776 0.024337
Cluster_245 Stenochlaena palustris 2.94 % 2.9e-05 0.000368
Cluster_442 Stenochlaena palustris 2.6 % 3.7e-05 0.001062
Cluster_255 Dicranopteris curranii 0.8 % 0.014349 0.026827
Cluster_249 Alsophila spinulosa 1.85 % 0.006027 0.0282
Sequences (2366) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms