AT3G18524 (ATMSH2, MSH2)

Aliases : ATMSH2, MSH2

Description : MUTS homolog 2

Gene families : OG0004193 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0004193_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT3G18524
Cluster	HCCA: Cluster_85

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00007p00236950	ATMSH2, MSH2,...	DNA damage response.DNA repair mechanisms.mismatch...	0.15	OrthoFinder output from all 47 species
Aspi01Gene34053.t1	ATMSH2, MSH2,...	component *(MSH2) of MSH2-x mismatch repair heterodimers...	0.03	OrthoFinder output from all 47 species
Cpa\|evm.model.tig00001224.8	ATMSH2, MSH2	DNA damage response.DNA repair mechanisms.mismatch...	0.07	OrthoFinder output from all 47 species
Cre01.g003463	ATMSH2, MSH2	DNA mismatch repair protein MSH2 OS=Zea mays	0.05	OrthoFinder output from all 47 species
Dac_g10467	ATMSH2, MSH2	component *(MSH2) of MSH2-x mismatch repair heterodimers...	0.02	OrthoFinder output from all 47 species
Gb_33909	ATMSH2, MSH2	component MSH2 of MSH2-x mismatch repair heterodimers	0.05	OrthoFinder output from all 47 species
LOC_Os05g19270.1	ATMSH2, MSH2,...	component MSH2 of MSH2-x mismatch repair heterodimers	0.03	OrthoFinder output from all 47 species
MA_10431416g0010	ATMSH2, MSH2	DNA mismatch repair protein MSH2 OS=Zea mays...	0.07	OrthoFinder output from all 47 species
MA_59360g0010	ATMSH2, MSH2	component MSH2 of MSH2-x mismatch repair heterodimers	0.12	OrthoFinder output from all 47 species
Mp4g08420.1	ATMSH2, MSH2	component MSH2 of MSH2-x mismatch repair heterodimers	0.09	OrthoFinder output from all 47 species
Smo407609	ATMSH2, MSH2	DNA mismatch repair protein MSH2 OS=Arabidopsis thaliana	0.03	OrthoFinder output from all 47 species
Solyc06g069230.3.1	ATMSH2, MSH2,...	component MSH2 of MSH2-x mismatch repair heterodimers	0.08	OrthoFinder output from all 47 species
Zm00001e035455_P001	ATMSH2, MSH2,...	component MSH2 of MSH2-x mismatch repair heterodimers	0.03	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
BP	GO:0000018	regulation of DNA recombination	None	Extended
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0000217	DNA secondary structure binding	None	Extended
CC	GO:0000228	nuclear chromosome	IBA	Interproscan
MF	GO:0000400	four-way junction DNA binding	IBA	Interproscan
MF	GO:0000403	Y-form DNA binding	IBA	Interproscan
MF	GO:0000404	heteroduplex DNA loop binding	IBA	Interproscan
MF	GO:0000406	double-strand/single-strand DNA junction binding	IBA	Interproscan
BP	GO:0000710	meiotic mismatch repair	IBA	Interproscan
BP	GO:0000724	double-strand break repair via homologous recombination	RCA	Interproscan
BP	GO:0000725	recombinational repair	None	Extended
BP	GO:0003006	developmental process involved in reproduction	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IDA	Interproscan
MF	GO:0003684	damaged DNA binding	ISS	Interproscan
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	Interproscan
MF	GO:0005524	ATP binding	ISS	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISM	Interproscan
CC	GO:0005694	chromosome	None	Extended
CC	GO:0005886	plasma membrane	IDA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006270	DNA replication initiation	RCA	Interproscan
BP	GO:0006275	regulation of DNA replication	RCA	Interproscan
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006290	pyrimidine dimer repair	IMP	Interproscan
BP	GO:0006298	mismatch repair	IMP	Interproscan
BP	GO:0006298	mismatch repair	ISS	Interproscan
BP	GO:0006301	postreplication repair	IBA	Interproscan
BP	GO:0006302	double-strand break repair	None	Extended
BP	GO:0006304	DNA modification	None	Extended
BP	GO:0006305	DNA alkylation	None	Extended
BP	GO:0006306	DNA methylation	RCA	Interproscan
BP	GO:0006310	DNA recombination	None	Extended
BP	GO:0006311	meiotic gene conversion	IBA	Interproscan
BP	GO:0006325	chromatin organization	None	Extended
BP	GO:0006338	chromatin remodeling	None	Extended
BP	GO:0006346	DNA methylation-dependent heterochromatin formation	RCA	Interproscan
BP	GO:0006479	protein methylation	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0006996	organelle organization	None	Extended
MF	GO:0008094	ATP-dependent activity, acting on DNA	IBA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008213	protein alkylation	None	Extended
BP	GO:0008283	cell population proliferation	RCA	Interproscan
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009909	regulation of flower development	RCA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010520	regulation of reciprocal meiotic recombination	None	Extended
BP	GO:0010564	regulation of cell cycle process	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0010639	negative regulation of organelle organization	None	Extended
BP	GO:0010948	negative regulation of cell cycle process	None	Extended
CC	GO:0016020	membrane	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0016570	histone modification	RCA	Interproscan
BP	GO:0016571	histone methylation	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
BP	GO:0018022	peptidyl-lysine methylation	None	Extended
BP	GO:0018193	peptidyl-amino acid modification	None	Extended
BP	GO:0018205	peptidyl-lysine modification	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0022414	reproductive process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IDA	Interproscan
BP	GO:0031047	RNA-mediated gene silencing	RCA	Interproscan
BP	GO:0031048	RNA-mediated heterochromatin formation	RCA	Interproscan
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031324	negative regulation of cellular metabolic process	None	Extended
BP	GO:0031507	heterochromatin formation	RCA	Interproscan
MF	GO:0032135	DNA insertion or deletion binding	None	Extended
MF	GO:0032137	guanine/thymine mispair binding	IBA	Interproscan
MF	GO:0032138	single base insertion or deletion binding	IBA	Interproscan
BP	GO:0032259	methylation	None	Extended
CC	GO:0032300	mismatch repair complex	None	Extended
CC	GO:0032301	MutSalpha complex	IBA	Interproscan
CC	GO:0032302	MutSbeta complex	IBA	Interproscan
BP	GO:0032502	developmental process	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033043	regulation of organelle organization	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034968	histone lysine methylation	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
BP	GO:0035822	gene conversion	None	Extended
BP	GO:0035825	homologous recombination	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0036211	protein modification process	None	Extended
BP	GO:0040020	regulation of meiotic nuclear division	None	Extended
BP	GO:0040029	epigenetic regulation of gene expression	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043414	macromolecule methylation	None	Extended
BP	GO:0043570	maintenance of DNA repeat elements	IBA	Interproscan
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044728	DNA methylation or demethylation	None	Extended
BP	GO:0045128	negative regulation of reciprocal meiotic recombination	IMP	Interproscan
BP	GO:0045786	negative regulation of cell cycle	None	Extended
BP	GO:0045787	positive regulation of cell cycle	RCA	Interproscan
BP	GO:0045814	negative regulation of gene expression, epigenetic	None	Extended
BP	GO:0045835	negative regulation of meiotic nuclear division	None	Extended
BP	GO:0045910	negative regulation of DNA recombination	None	Extended
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0048449	floral organ formation	RCA	Interproscan
BP	GO:0048451	petal formation	RCA	Interproscan
BP	GO:0048453	sepal formation	RCA	Interproscan
BP	GO:0048518	positive regulation of biological process	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048522	positive regulation of cellular process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0048580	regulation of post-embryonic development	None	Extended
BP	GO:0048646	anatomical structure formation involved in morphogenesis	None	Extended
BP	GO:0048831	regulation of shoot system development	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050793	regulation of developmental process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051053	negative regulation of DNA metabolic process	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051129	negative regulation of cellular component organization	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051239	regulation of multicellular organismal process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0051445	regulation of meiotic cell cycle	None	Extended
BP	GO:0051447	negative regulation of meiotic cell cycle	None	Extended
BP	GO:0051567	histone H3-K9 methylation	RCA	Interproscan
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0051726	regulation of cell cycle	RCA	Interproscan
BP	GO:0051783	regulation of nuclear division	None	Extended
BP	GO:0051784	negative regulation of nuclear division	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0061647	histone H3-K9 modification	None	Extended
BP	GO:0061982	meiosis I cell cycle process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0070828	heterochromatin organization	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
CC	GO:0140513	nuclear protein-containing complex	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
MF	GO:0140657	ATP-dependent activity	None	Extended
BP	GO:0140718	facultative heterochromatin formation	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1903046	meiotic cell cycle process	None	Extended
BP	GO:1905393	plant organ formation	None	Extended
BP	GO:2000026	regulation of multicellular organismal development	None	Extended
BP	GO:2000241	regulation of reproductive process	None	Extended
BP	GO:2000242	negative regulation of reproductive process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000226	microtubule cytoskeleton organization	IEP	HCCA
BP	GO:0000723	telomere maintenance	IEP	HCCA
CC	GO:0000793	condensed chromosome	IEP	HCCA
CC	GO:0000794	condensed nuclear chromosome	IEP	HCCA
CC	GO:0000796	condensin complex	IEP	HCCA
BP	GO:0000910	cytokinesis	IEP	HCCA
BP	GO:0000911	cytokinesis by cell plate formation	IEP	HCCA
BP	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis	IEP	HCCA
BP	GO:0000914	phragmoplast assembly	IEP	HCCA
BP	GO:0001708	cell fate specification	IEP	HCCA
MF	GO:0003774	cytoskeletal motor activity	IEP	HCCA
MF	GO:0003777	microtubule motor activity	IEP	HCCA
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	HCCA
MF	GO:0004527	exonuclease activity	IEP	HCCA
MF	GO:0004529	exodeoxyribonuclease activity	IEP	HCCA
MF	GO:0004536	deoxyribonuclease activity	IEP	HCCA
CC	GO:0005657	replication fork	IEP	HCCA
CC	GO:0005874	microtubule	IEP	HCCA
BP	GO:0006260	DNA replication	IEP	HCCA
BP	GO:0006261	DNA-templated DNA replication	IEP	HCCA
BP	GO:0006268	DNA unwinding involved in DNA replication	IEP	HCCA
BP	GO:0006279	premeiotic DNA replication	IEP	HCCA
BP	GO:0006287	base-excision repair, gap-filling	IEP	HCCA
BP	GO:0006297	nucleotide-excision repair, DNA gap filling	IEP	HCCA
BP	GO:0006312	mitotic recombination	IEP	HCCA
BP	GO:0007010	cytoskeleton organization	IEP	HCCA
BP	GO:0007017	microtubule-based process	IEP	HCCA
BP	GO:0007020	microtubule nucleation	IEP	HCCA
BP	GO:0007062	sister chromatid cohesion	IEP	HCCA
BP	GO:0007154	cell communication	IEP	HCCA
BP	GO:0007275	multicellular organism development	IEP	HCCA
BP	GO:0007346	regulation of mitotic cell cycle	IEP	HCCA
MF	GO:0008296	3'-5'-exodeoxyribonuclease activity	IEP	HCCA
MF	GO:0008408	3'-5' exonuclease activity	IEP	HCCA
BP	GO:0009553	embryo sac development	IEP	HCCA
BP	GO:0009615	response to virus	IEP	HCCA
BP	GO:0009957	epidermal cell fate specification	IEP	HCCA
BP	GO:0010267	ta-siRNA processing	IEP	HCCA
BP	GO:0010332	response to gamma radiation	IEP	HCCA
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	IEP	HCCA
BP	GO:0016444	somatic cell DNA recombination	IEP	HCCA
BP	GO:0016458	obsolete gene silencing	IEP	HCCA
BP	GO:0016572	obsolete histone phosphorylation	IEP	HCCA
MF	GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	HCCA
MF	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	IEP	HCCA
BP	GO:0019722	calcium-mediated signaling	IEP	HCCA
BP	GO:0019932	second-messenger-mediated signaling	IEP	HCCA
BP	GO:0030261	chromosome condensation	IEP	HCCA
BP	GO:0030422	siRNA processing	IEP	HCCA
BP	GO:0031109	microtubule polymerization or depolymerization	IEP	HCCA
BP	GO:0032200	telomere organization	IEP	HCCA
BP	GO:0032204	regulation of telomere maintenance	IEP	HCCA
BP	GO:0032392	DNA geometric change	IEP	HCCA
BP	GO:0032506	cytokinetic process	IEP	HCCA
BP	GO:0032508	DNA duplex unwinding	IEP	HCCA
BP	GO:0033260	nuclear DNA replication	IEP	HCCA
MF	GO:0034061	DNA polymerase activity	IEP	HCCA
BP	GO:0034470	ncRNA processing	IEP	HCCA
BP	GO:0034660	ncRNA metabolic process	IEP	HCCA
BP	GO:0035196	miRNA processing	IEP	HCCA
CC	GO:0042575	DNA polymerase complex	IEP	HCCA
BP	GO:0042631	cellular response to water deprivation	IEP	HCCA
BP	GO:0043137	DNA replication, removal of RNA primer	IEP	HCCA
BP	GO:0043247	telomere maintenance in response to DNA damage	IEP	HCCA
CC	GO:0043625	delta DNA polymerase complex	IEP	HCCA
CC	GO:0044815	DNA packaging complex	IEP	HCCA
BP	GO:0045004	DNA replication proofreading	IEP	HCCA
BP	GO:0045005	DNA-templated DNA replication maintenance of fidelity	IEP	HCCA
BP	GO:0046785	microtubule polymerization	IEP	HCCA
BP	GO:0048229	gametophyte development	IEP	HCCA
BP	GO:0048768	root hair cell tip growth	IEP	HCCA
BP	GO:0051258	protein polymerization	IEP	HCCA
BP	GO:0051607	defense response to virus	IEP	HCCA
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	HCCA
BP	GO:0070918	regulatory ncRNA processing	IEP	HCCA
BP	GO:0071103	DNA conformation change	IEP	HCCA
BP	GO:0071229	cellular response to acid chemical	IEP	HCCA
BP	GO:0071462	cellular response to water stimulus	IEP	HCCA
CC	GO:0099080	supramolecular complex	IEP	HCCA
CC	GO:0099081	supramolecular polymer	IEP	HCCA
CC	GO:0099512	supramolecular fiber	IEP	HCCA
CC	GO:0099513	polymeric cytoskeletal fiber	IEP	HCCA
BP	GO:0140546	defense response to symbiont	IEP	HCCA
BP	GO:1901987	regulation of cell cycle phase transition	IEP	HCCA
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	HCCA
BP	GO:1902407	assembly of actomyosin apparatus involved in mitotic cytokinesis	IEP	HCCA
BP	GO:1902410	mitotic cytokinetic process	IEP	HCCA
BP	GO:1902749	regulation of cell cycle G2/M phase transition	IEP	HCCA
BP	GO:1903047	mitotic cell cycle process	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR007695	DNA_mismatch_repair_MutS-lik_N	23	128
IPR000432	DNA_mismatch_repair_MutS_C	662	858
IPR007696	DNA_mismatch_repair_MutS_core	299	606
IPR007861	DNA_mismatch_repair_MutS_clamp	469	563
IPR007860	DNA_mmatch_repair_MutS_con_dom	144	283

External Links

No external refs found!

AT3G18524 (ATMSH2, MSH2)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation