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GO:0000124: SAGA complex (Cellular component)

"A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695)." [PMID:10637607, PMID:17337012, PMID:19056896, PMID:20838651, PMID:33004486]


There are 780 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_80 Chlamydomonas reinhardtii 1.59 % 0.003551 0.034893
Cluster_135 Cyanophora paradoxa 1.82 % 0.004448 0.023353
Cluster_13 Cyanophora paradoxa 0.57 % 0.014199 0.048553
Cluster_165 Marchantia polymorpha 1.61 % 0.006375 0.041766
Cluster_170 Marchantia polymorpha 1.47 % 0.006991 0.04585
Cluster_151 Physcomitrella patens 0.97 % 0.003173 0.034907
Cluster_226 Vitis vinifera 1.82 % 0.002088 0.038447
Cluster_51 Zea mays 0.55 % 0.008688 0.036827
Cluster_415 Picea abies 0.95 % 0.001576 0.03782
Cluster_116 Amblovenatum opulentum 1.82 % 0.002306 0.011606
Cluster_600 Amblovenatum opulentum 1.82 % 0.002306 0.041095
Cluster_292 Angiopteris evecta 0.64 % 0.003146 0.01965
Cluster_239 Microlepia speluncae 1.64 % 0.003734 0.033603
Cluster_92 Salvinia molesta 1.49 % 0.005031 0.04668
Cluster_181 Tectaria incisa 0.68 % 0.003136 0.019745
Cluster_226 Diplazium proliferum (Lam.) Kaulf. 0.87 % 0.002474 0.034897
Cluster_481 Ophioglossum reticulatum 1.72 % 0.001271 0.02717
Cluster_324 Stenochlaena palustris 0.93 % 0.005628 0.04018
Cluster_453 Stenochlaena palustris 1.3 % 0.004015 0.024837
Sequences (780) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms