1. Home
  2. GO
  3. GO:0000124

GO:0000124: SAGA complex (Cellular component)

"A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695)." [PMID:10637607, PMID:17337012, PMID:19056896, PMID:20838651, PMID:33004486]


There are 780 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_229 Actinostachys digitata 0.77 % 0.003986 0.043465
Cluster_116 Amblovenatum opulentum 2.08 % 0.002013 0.012078
Cluster_98 Ginkgo biloba 1.39 % 0.003483 0.024222
Cluster_181 Tectaria incisa 0.8 % 0.002685 0.017427
Sequences (780) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms