Description : 27.2 RNA.transcription This gene encodes the second largest, catalytic subunit of the nuclear DNA-dependent RNA polymerase IV (aka RNA polymerase D). The NRPD2 protein is found at nuclear foci that overlap or are adjacent to chromocentromeres but are not fully coincident with chromocentromeres. The loss of NRPD2 leads to the loss of cytosine methylation at pericentromeric 5S genes and AtSN1 retroelements but has no discernible effect on centromere repeat methylation. This suggests that Pol IV primarily affects facultative heterochromatin rather than constitutive heterochromatin. nuclear RNA polymerase D2A (NRPD2A)
Gene families : OG_01_0062273 (Gene family) Phylogenetic Tree(s): No tree available for this family
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | HRR network (cutoff 100): MA_10208460g0010 | |
Cluster | HCCA cluster: Cluster_8 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003677 | DNA binding | IEA | InterProScan |
MF | GO:0003899 | DNA-directed 5'-3' RNA polymerase activity | IEA | InterProScan |
BP | GO:0006351 | transcription, DNA-templated | IEA | InterProScan |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
No Predicted GO terms available for this sequence |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR007642 | RNA_pol_Rpb2_2 | 27 | 165 |
No external refs found! |