Tin_g17142 (MLH1, ATMLH1)

Aliases : MLH1, ATMLH1

Description : component *(MLH1) of MLH1-PMS1 heterodimer & original description: none

Gene families : OG0003563 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0003563_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Tin_g17142

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00071p00146130	MLH1, ATMLH1,...	DNA damage response.DNA repair mechanisms.mismatch...	0.02	OrthoFinder output from all 47 species
AT4G09140	MLH1, ATMLH1	MUTL-homologue 1	0.04	OrthoFinder output from all 47 species
Aop_g00761	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.02	OrthoFinder output from all 47 species
GSVIVT01026715001	MLH1, ATMLH1	DNA damage response.DNA repair mechanisms.mismatch...	0.02	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001522	pseudouridine synthesis	IEP	HCCA
MF	GO:0003723	RNA binding	IEP	HCCA
MF	GO:0003746	translation elongation factor activity	IEP	HCCA
BP	GO:0006414	translational elongation	IEP	HCCA
BP	GO:0008064	regulation of actin polymerization or depolymerization	IEP	HCCA
MF	GO:0008135	translation factor activity, RNA binding	IEP	HCCA
MF	GO:0008270	zinc ion binding	IEP	HCCA
CC	GO:0008290	F-actin capping protein complex	IEP	HCCA
BP	GO:0009451	RNA modification	IEP	HCCA
MF	GO:0009982	pseudouridine synthase activity	IEP	HCCA
BP	GO:0010639	negative regulation of organelle organization	IEP	HCCA
BP	GO:0016042	lipid catabolic process	IEP	HCCA
MF	GO:0016866	intramolecular transferase activity	IEP	HCCA
BP	GO:0030832	regulation of actin filament length	IEP	HCCA
BP	GO:0030833	regulation of actin filament polymerization	IEP	HCCA
BP	GO:0030834	regulation of actin filament depolymerization	IEP	HCCA
BP	GO:0030835	negative regulation of actin filament depolymerization	IEP	HCCA
BP	GO:0030837	negative regulation of actin filament polymerization	IEP	HCCA
BP	GO:0031333	negative regulation of protein-containing complex assembly	IEP	HCCA
BP	GO:0032271	regulation of protein polymerization	IEP	HCCA
BP	GO:0032272	negative regulation of protein polymerization	IEP	HCCA
BP	GO:0032535	regulation of cellular component size	IEP	HCCA
BP	GO:0032956	regulation of actin cytoskeleton organization	IEP	HCCA
BP	GO:0032970	regulation of actin filament-based process	IEP	HCCA
BP	GO:0033043	regulation of organelle organization	IEP	HCCA
MF	GO:0042393	histone binding	IEP	HCCA
BP	GO:0043242	negative regulation of protein-containing complex disassembly	IEP	HCCA
BP	GO:0043244	regulation of protein-containing complex disassembly	IEP	HCCA
BP	GO:0043254	regulation of protein-containing complex assembly	IEP	HCCA
BP	GO:0044087	regulation of cellular component biogenesis	IEP	HCCA
MF	GO:0045182	translation regulator activity	IEP	HCCA
BP	GO:0048519	negative regulation of biological process	IEP	HCCA
BP	GO:0048523	negative regulation of cellular process	IEP	HCCA
BP	GO:0050794	regulation of cellular process	IEP	HCCA
BP	GO:0051016	barbed-end actin filament capping	IEP	HCCA
BP	GO:0051128	regulation of cellular component organization	IEP	HCCA
BP	GO:0051129	negative regulation of cellular component organization	IEP	HCCA
BP	GO:0051493	regulation of cytoskeleton organization	IEP	HCCA
BP	GO:0051494	negative regulation of cytoskeleton organization	IEP	HCCA
BP	GO:0051693	actin filament capping	IEP	HCCA
BP	GO:0065008	regulation of biological quality	IEP	HCCA
BP	GO:0090066	regulation of anatomical structure size	IEP	HCCA
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	HCCA
BP	GO:0110053	regulation of actin filament organization	IEP	HCCA
BP	GO:1901879	regulation of protein depolymerization	IEP	HCCA
BP	GO:1901880	negative regulation of protein depolymerization	IEP	HCCA
BP	GO:1902903	regulation of supramolecular fiber organization	IEP	HCCA
BP	GO:1902904	negative regulation of supramolecular fiber organization	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR032189	Mlh1_C	441	731
IPR013507	DNA_mismatch_S5_2-like	226	346

External Links

No external refs found!

Tin_g17142 (MLH1, ATMLH1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation