Aliases : PACid_15415012
Description : 188.8.131.52 protein.degradation.ubiquitin.E2 MMZ3/UEV1C encodes a protein that may play a role in DNA damage responses and error-free post-replicative DNA repair by participating in lysine-63-based polyubiquitination reactions. UEV1C can form diubiquitin and triubiquitin chains in combination with UBC13A/UBC35 in vitro. It can also functionally complement an mms2 mutation in budding yeast, both by increasing mms2 mutant viability in the presence of the DNA damaging agent MMS, and by reducing the rate of spontaneous DNA mutation. It can also rescue an mms2 ubc13 double mutant in yeast in combination with UBC13A. MMZ3/UEV1C transcripts are found at moderate levels in most plant organs, but cannot be detected in the pollen or 2 days after germination. Transcript levels do not appear to be stress-inducible. MMS ZWEI homologue 3 (MMZ3) CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608) BEST Arabidopsis thaliana protein match is: ubiquitin E2 variant 1D-4 (TAIR:AT3G52560.1) Has 2913 Blast hits to 2913 proteins in 284 species: Archae - 0 Bacteria - 0 Metazoa - 1555 Fungi - 342 Plants - 599 Viruses - 0 Other Eukaryotes - 417 (source: NCBI BLink). & (loc_os12g41220.1 : 208.0
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
|Neighborhood||HRR network (cutoff 100): Smo268551|
|Cluster||HCCA cluster: Cluster_83|
|Target||Alias||Description||ECC score||Gene Family Method||Actions|
|Smo270524||PACid_15420970||184.108.40.206 protein.degradation.ubiquitin.E2 MMZ3/UEV1C...||0.03||Gene family|
|No external refs found!|