Description : 33.99 development.unspecified Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1. MULTICOPY SUPRESSOR OF IRA1 (MSI1)

Gene families : OG_01_0001663 (Gene family) Phylogenetic Tree(s): OG0001663_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type Description Actions
Neighborhood HRR network (cutoff 100): Cre12.g523200
Cluster HCCA cluster: Cluster_38

Target Alias Description ECC score Gene Family Method Actions
AT2G16780 MSI2, NFC2, NFC02, MSI02 Transducin family protein / WD-40 repeat family protein 0.05 Gene family
GSVIVT01024023001 No alias 33.99 development.unspecified Encodes a WD-40 repeat... 0.02 Gene family
LOC_Os03g43890 Os03g0640100 33.99 development.unspecified Encodes a WD-40 repeat... 0.02 Gene family
LOC_Os09g36900 Os09g0540600 33.99 development.unspecified Encodes a WD-40 repeat... 0.03 Gene family
Zm00001d022614 GRMZM2G032711 33.99 development.unspecified Encodes a WD-40 repeat... 0.04 Gene family

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR001680 WD40_repeat 309 347
IPR001680 WD40_repeat 272 301
IPR001680 WD40_repeat 368 403
IPR001680 WD40_repeat 171 207
IPR022052 Histone-bd_RBBP4_N 19 88
No external refs found!