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Azfi_s0319.g064441 details<li class="active"><strong> Adi_g082854</strong></li></ol><h1><strong>Adi_g082854</strong> <small>(GRF10, GF14 EPSILON,...)</small></h1><br><p><strong>Aliases :</strong> GRF10, GF14 EPSILON, 14-3-3EPSILON</p><p><strong>Description :</strong> not classified & original description: none</p><br><div><p><strong><abbr title="Click to show help" href="/help/gene_family" data-target="#helpModal">Gene families</abbr> :</strong><a href="/family/view/1240852"> OG0011251</a> (OrthoFinder output from all 47 species) Phylogenetic Tree(s):<a href="/tree/view/652931"> OG0011251_tree</a></p><p><strong>Sequence :</strong><a href="/sequence/modal/coding/2514305" data-target="#profileModal">coding</a> (<a href="/sequence/fasta/coding/2514305">download</a>),<a href="/sequence/modal/protein/2514305" data-target="#profileModal"> protein</a> (<a href="/sequence/fasta/protein/2514305">download</a>)</p></div><h3 class="banner-blue" id="expression_profile"> Expression Profile</h3><div class="pull-right"><a href="#" class="btn btn-default" id="enable_pan" data-toggle="tooltip" title="Toggle Pan"><i class="fa fa-arrows" aria-hidden="true"></i></a><a href="#" class="btn btn-default" id="enable_zoom" data-toggle="tooltip" title="Toggle zoom"><i class="fa fa-search" aria-hidden="true"></i></a></div><div style="height:550px; max-height:550px; margin-top:30px"><canvas id="expression-profile" class="center-block" height="550"/></div><br><div class="pull-right"><a href="/profile/download/plot/2311768" class="btn btn-primary" download="plot_2311768.txt">Download</a></div><p><strong>Note:</strong>Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available<a href="/profile/view/2311768"> here</a>.</p><br><div><h3 class="banner-blue" id="coexpression_networks">Co-expression Networks</h3><div class="table-responsive"><table class="table table-striped table-separated" id="coexpression_table"><thead><tr><th data-sort="string-ins"><span class="sort-icon"></span>Type</th><th data-sort="string-ins"><span class="sort-icon"></span>Description</th><th>Actions</th></tr></thead><tbody><tr><td><abbr title="Click to show help" href="/help/neighborhood" data-target="#helpModal">Neighborhood</abbr></td><td>HRR:<strong> Adi_g082854</strong></td><td><a href="/network/download/neighbors/2710661" data-toggle="tooltip" data-placement="top" title="Download direct neighbors" download="neighbors_2710661.txt"><i class="fa fa-list"></i></span><a href="/network/graph/2710661" data-toggle="tooltip" data-placement="top" title="View neighborhood as graph"><i class="fa fa-sitemap"></i></a><span class="text-muted" data-toggle="tooltip" data-placement="top" title="Disabled for neighborhoods"><i class="fa fa-area-chart"></i></span><span class="text-muted" data-toggle="tooltip" data-placement="top" title="Disabled for neighborhoods"><i class="fa fa-table"></i></span></td></tr></tbody></table></div></div><br><h3 class="banner-blue" id="expression_conservation">Expression Context Conservation (<abbr title="Click to show help" href="/help/ecc" data-target="#helpModal">ECC</abbr>)</h3><div class="table-responsive"><table class="table table-striped table-separated" id="ecc_hits_table"><thead><tr><th data-sort="string-ins"><span class="sort-icon"></span>Target</th><th data-sort="string-ins"><span class="sort-icon"></span>Alias</th><th data-sort="string-ins"><span class="sort-icon"></span>Description</th><th data-sort="float"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/ecc" data-target="#helpModal">ECC</abbr> score</th><th data-sort="string-ins"><span class="sort-icon"></span>Gene Family Method</th><th>Actions</th></tr></thead><tbody><tr><td><a href="/sequence/view/1946277" class="qtip_tooltip qtip_dynamic_tooltip" qtip_href="/sequence/tooltip/1946277">Ppi_g11628</a></td><td>GRF12, GF14 IOTA</td><td>not classified & original description: none</td><td>0.01</td><td>OrthoFinder output from all 47 species</td><td><a href="/ecc/graph_pair/43542178" data-toggle="tooltip" data-placement="top" title="View ECC pair as graph"><i class="fa fa-eye"></i></a><a href="/ecc/graph/2514305/56/21" data-toggle="tooltip" data-placement="top" title="View ECC as graph"><i class="fa fa-sitemap"></i></a></td></tr></tbody></table></div><br><h3 class="banner-blue" id="annotation">Functional Annotation</h3><div class="panel with-nav-tabs panel-default"><div class="panel-heading"><ul class="nav nav-tabs"><li class="active"><a href="#tab1default" data-toggle="tab">GO</a></li><li><a href="#tab2default" data-toggle="tab">Predicted GO</a></li><li><a href="#tab3default" data-toggle="tab">InterPro</a></li></ul></div><div><div class="tab-content"><div class="tab-pane fade in active" id="tab1default"><div class="table-responsive"><table class="table table-striped table-fixed" id="go_table"><thead><tr><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Type</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/go" data-target="#helpModal">GO</abbr> Term</th><th class="col-xs-6" data-sort="string-ins"><span class="sort-icon"></span>Name</th><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Evidence</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span>Source</th></tr></thead><tbody><tr><td class="col-xs-12"><p>No GO annotation available for this sequence</p></td></tr></tbody></table></div><div class="panel-body"><a href="#" id="go_toggle">Toggle parental</a></div></div><div class="tab-pane fade" id="tab2default"><div class="table-responsive"><table class="table table-striped table-fixed" id="predicted_go_table"><thead><tr><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Type</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/go" data-target="#helpModal">GO</abbr> Term</th><th class="col-xs-6" data-sort="string-ins"><span class="sort-icon"></span>Name</th><th class="col-xs-1" data-sort="string-ins"><span class="sort-icon"></span>Evidence</th><th class="col-xs-2" data-sort="string-ins"><span class="sort-icon"></span>Source</th></tr></thead><tbody><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/3628" data-toggle="tooltip" data-placement="top" title=""An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated." [GOC:jh2, PMID:30783221]">GO:0004843</a></td><td class="col-xs-6">cysteine-type deubiquitinase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/4986" data-toggle="tooltip" data-placement="top" title=""The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds." [GOC:bf, GOC:mah]">GO:0006508</a></td><td class="col-xs-6">proteolysis</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/4989" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein." [GOC:go_curators]">GO:0006511</a></td><td class="col-xs-6">ubiquitin-dependent protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/6054" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament." [GOC:mah]">GO:0008064</a></td><td class="col-xs-6">regulation of actin polymerization or depolymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/6130" data-toggle="tooltip" data-placement="top" title=""A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt]">GO:0008150</a></td><td class="col-xs-6">biological_process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/6147" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a methyl group to an acceptor molecule." [ISBN:0198506732]">GO:0008168</a></td><td class="col-xs-6">methyltransferase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/6207" data-toggle="tooltip" data-placement="top" title=""Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]">GO:0008234</a></td><td class="col-xs-6">cysteine-type peptidase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/6256" data-toggle="tooltip" data-placement="top" title=""A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments." [GOC:go_curators, ISBN:0198599560]">GO:0008290</a></td><td class="col-xs-6">F-actin capping protein complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/6929" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684]">GO:0009056</a></td><td class="col-xs-6">catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/6930" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah]">GO:0009057</a></td><td class="col-xs-6">macromolecule catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/7802" data-toggle="tooltip" data-placement="top" title=""Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete]">GO:0009987</a></td><td class="col-xs-6">cellular process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/8419" data-toggle="tooltip" data-placement="top" title=""Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb]">GO:0010639</a></td><td class="col-xs-6">negative regulation of organelle organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/10464" data-toggle="tooltip" data-placement="top" title=""Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732]">GO:0016741</a></td><td class="col-xs-6">transferase activity, transferring one-carbon groups</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/12463" data-toggle="tooltip" data-placement="top" title=""The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus." [GOC:jl, GOC:mtg_sensu, GOC:rb, PMID:10854779]">GO:0019773</a></td><td class="col-xs-6">proteasome core complex, alpha-subunit complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/12473" data-toggle="tooltip" data-placement="top" title=""An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins." [PMID:19489724]">GO:0019783</a></td><td class="col-xs-6">ubiquitin-like protein peptidase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/12619" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein." [GOC:go_curators]">GO:0019941</a></td><td class="col-xs-6">modification-dependent protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/14136" data-toggle="tooltip" data-placement="top" title=""Any process that controls the length of actin filaments in a cell." [GOC:dph, GOC:mah]">GO:0030832</a></td><td class="col-xs-6">regulation of actin filament length</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/14137" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament." [GOC:mah]">GO:0030833</a></td><td class="col-xs-6">regulation of actin filament polymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/14138" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament." [GOC:mah]">GO:0030834</a></td><td class="col-xs-6">regulation of actin filament depolymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/14139" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization." [GOC:mah]">GO:0030835</a></td><td class="col-xs-6">negative regulation of actin filament depolymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/14141" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization." [GOC:mah]">GO:0030837</a></td><td class="col-xs-6">negative regulation of actin filament polymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/14592" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah]">GO:0031333</a></td><td class="col-xs-6">negative regulation of protein-containing complex assembly</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/15479" data-toggle="tooltip" data-placement="top" title=""The process in which a methyl group is covalently attached to a molecule." [GOC:mah]">GO:0032259</a></td><td class="col-xs-6">methylation</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/15488" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]">GO:0032271</a></td><td class="col-xs-6">regulation of protein polymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/15489" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah]">GO:0032272</a></td><td class="col-xs-6">negative regulation of protein polymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/15729" data-toggle="tooltip" data-placement="top" title=""A process that modulates the size of a cellular component." [GOC:mah]">GO:0032535</a></td><td class="col-xs-6">regulation of cellular component size</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/16121" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah]">GO:0032956</a></td><td class="col-xs-6">regulation of actin cytoskeleton organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/16135" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah]">GO:0032970</a></td><td class="col-xs-6">regulation of actin filament-based process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">CC</td><td class="col-xs-2"><a href="/go/view/16156" data-toggle="tooltip" data-placement="top" title=""A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah]">GO:0032991</a></td><td class="col-xs-6">protein-containing complex</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/16207" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah]">GO:0033043</a></td><td class="col-xs-6">regulation of organelle organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21072" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl]">GO:0043242</a></td><td class="col-xs-6">negative regulation of protein-containing complex disassembly</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21074" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl]">GO:0043244</a></td><td class="col-xs-6">regulation of protein-containing complex disassembly</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21084" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl]">GO:0043254</a></td><td class="col-xs-6">regulation of protein-containing complex assembly</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21425" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule." [GOC:jl]">GO:0043632</a></td><td class="col-xs-6">modification-dependent macromolecule catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21848" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl]">GO:0044087</a></td><td class="col-xs-6">regulation of cellular component biogenesis</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21987" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:jl]">GO:0044248</a></td><td class="col-xs-6">cellular catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/21997" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells." [GOC:jl]">GO:0044265</a></td><td class="col-xs-6">cellular macromolecule catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/24232" data-toggle="tooltip" data-placement="top" title=""The directed movement of substances within a cell." [GOC:ai]">GO:0046907</a></td><td class="col-xs-6">intracellular transport</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/25728" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid]">GO:0048519</a></td><td class="col-xs-6">negative regulation of biological process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/25732" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid]">GO:0048523</a></td><td class="col-xs-6">negative regulation of cellular process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27092" data-toggle="tooltip" data-placement="top" title=""The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X]">GO:0051016</a></td><td class="col-xs-6">barbed-end actin filament capping</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27200" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]">GO:0051128</a></td><td class="col-xs-6">regulation of cellular component organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27201" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai]">GO:0051129</a></td><td class="col-xs-6">negative regulation of cellular component organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/27351" data-toggle="tooltip" data-placement="top" title=""Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH." [GOC:ai]">GO:0051287</a></td><td class="col-xs-6">NAD binding</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27543" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]">GO:0051493</a></td><td class="col-xs-6">regulation of cytoskeleton organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27544" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai]">GO:0051494</a></td><td class="col-xs-6">negative regulation of cytoskeleton organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27638" data-toggle="tooltip" data-placement="top" title=""The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells." [GOC:ai, GOC:dph, GOC:tb]">GO:0051603</a></td><td class="col-xs-6">proteolysis involved in protein catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27683" data-toggle="tooltip" data-placement="top" title=""Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos, GOC:dph, GOC:tb]">GO:0051649</a></td><td class="col-xs-6">establishment of localization in cell</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/27724" data-toggle="tooltip" data-placement="top" title=""The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits." [ISBN:071673706X]">GO:0051693</a></td><td class="col-xs-6">actin filament capping</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/31039" data-toggle="tooltip" data-placement="top" title=""Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]">GO:0065008</a></td><td class="col-xs-6">regulation of biological quality</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/31430" data-toggle="tooltip" data-placement="top" title=""Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions." [GOC:mah]">GO:0070403</a></td><td class="col-xs-6">NAD+ binding</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/34370" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the size of an anatomical structure." [GOC:dph, GOC:tb]">GO:0090066</a></td><td class="col-xs-6">regulation of anatomical structure size</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">MF</td><td class="col-xs-2"><a href="/go/view/36664" data-toggle="tooltip" data-placement="top" title=""An isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated." [GOC:mec, PMID:30783221]">GO:0101005</a></td><td class="col-xs-6">deubiquitinase activity</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/38114" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of actin filament organization." [GOC:kmv]">GO:0110053</a></td><td class="col-xs-6">regulation of actin filament organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/41017" data-toggle="tooltip" data-placement="top" title=""The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie]">GO:1901575</a></td><td class="col-xs-6">organic substance catabolic process</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/41311" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137]">GO:1901879</a></td><td class="col-xs-6">regulation of protein depolymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/41312" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137]">GO:1901880</a></td><td class="col-xs-6">negative regulation of protein depolymerization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/42259" data-toggle="tooltip" data-placement="top" title=""Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]">GO:1902903</a></td><td class="col-xs-6">regulation of supramolecular fiber organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr><tr style="clear:both;"><td class="col-xs-1">BP</td><td class="col-xs-2"><a href="/go/view/42260" data-toggle="tooltip" data-placement="top" title=""Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388]">GO:1902904</a></td><td class="col-xs-6">negative regulation of supramolecular fiber organization</td><td class="col-xs-1">IEP</td><td class="col-xs-2">HCCA</td></tr></tbody></table></div></div><div class="tab-pane fade" id="tab3default"><div class="table-responsive"><table class="table table-striped table-fixed" id="interpro_table"><thead><tr><th class="col-xs-3" data-sort="string-ins"><span class="sort-icon"></span><abbr title="Click to show help" href="/help/interpro_domain" data-target="#helpModal">InterPro domains</abbr></th><th class="col-xs-5" data-sort="string-ins"><span class="sort-icon"></span>Description</th><th class="col-xs-2" data-sort="int"><span class="sort-icon"></span>Start</th><th class="col-xs-2" data-sort="int"><span class="sort-icon"></span>Stop</th></tr></thead><tbody><tr><td class="col-xs-3"><a href="/interpro/view/19626">IPR023410</a></td><td class="col-xs-5">14-3-3_domain</td><td class="col-xs-2">14</td><td class="col-xs-2">119</td></tr></tbody></table></div></div></div></div></div><div class="row"><div class="col-lg-12 col-md-12 col-sm-12"><div class="panel panel-default"><div class="panel-heading" id="links">External Links</div><div class="table-responsive"><table class="table table-striped table-separated"><tbody><tr><td><em>No external refs found!</em></td></td></tr></tbody></table></div></div></div></div><div class="modal" id="profileModal" tabindex="-1" role="dialog" aria-labelledby="profileModalLabel"><div class="modal-dialog" role="document" style="width:1000px;height:800px;"><div class="modal-content"></div></div></div></div></div></div><footer class="footer" id="footer"><div class="container"><div class="row"><div class="col-xs-2"><strong class="text-muted"><a href="/features" class="text-muted">CoNekT</a></strong></div><div class="col-xs-2"><a href="/about" class="text-muted">About</a></div><div class="col-xs-2"><a href="/contact" class="text-muted">Contact</a></div><div class="col-xs-2"><a href="/disclaimer" class="text-muted">Disclaimer</a></div><div class="col-xs-2"><a href="/privacy" class="text-muted">Privacy policy</a></div></div></div></footer><div class="modal" id="helpModal" tabindex="-1" role="dialog" aria-labelledby="helpModalLabel"><div class="modal-dialog" role="document" style="width:1000px;height:800px;"><div class="modal-content"></div></div></div><div class="modal" id="loaderModal" tabindex="-1" role="dialog" aria-labelledby="loaderModalLabel"><div class="modal-dialog" role="document" style="width:1000px;height:800px;"><div class="modal-content"><div class="modal-body"><div id="leafy_loader"></div><p class="text-center text-muted" id="leafy_loader_text">Loading ... please wait ...</p><p class="text-center" id="leafy_loader_close_btn" style="display:none"><button type="button" class="btn btn-primary" data-dismiss="modal" style> Close</button></p></div></div></div></div><script src="/static/js/jquery.min.js"></script><script src="/static/js/bootstrap.min.js"></script><script src="/static/js/stupidtable.min.js"></script><script src="/static/js/TweenMax.min.js"></script><script src="/static/js/jquery.qtip.min.js"></script><script src="/static/js/planet_loader.js"></script><script>
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