Spa_g25841 (MGO1, TOP1, TOP1ALPHA)

Aliases : MGO1, TOP1, TOP1ALPHA

Description : DNA topoisomerase *(TOP1) & original description: none

Gene families : OG0002461 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0002461_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Spa_g25841

Target	Alias	Description	ECC score	Gene Family Method
Adi_g104710	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.02	OrthoFinder output from all 47 species
Ala_g08299	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.03	OrthoFinder output from all 47 species
Als_g15949	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.03	OrthoFinder output from all 47 species
Aob_g41324	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.04	OrthoFinder output from all 47 species
Cba_g21831	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.04	OrthoFinder output from all 47 species
Ceric.31G042500.1	TOP1BETA, TOP1,...	DNA topoisomerase *(TOP1) & original description:...	0.04	OrthoFinder output from all 47 species
MA_120434g0010	TOP1BETA, TOP1	DNA topoisomerase (TOP1)	0.04	OrthoFinder output from all 47 species
Msp_g13694	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.03	OrthoFinder output from all 47 species
Ore_g41412	TOP1BETA, TOP1	DNA topoisomerase *(TOP1) & original description: none	0.03	OrthoFinder output from all 47 species
Smo109207	TOP1BETA, TOP1	Cell cycle.interphase.DNA replication.preinitiation.TOP1...	0.02	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I (single strand cut, ATP-independent) activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:0140640	catalytic activity, acting on a nucleic acid	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003684	damaged DNA binding	IEP	HCCA
CC	GO:0005634	nucleus	IEP	HCCA
BP	GO:0006281	DNA repair	IEP	HCCA
BP	GO:0006950	response to stress	IEP	HCCA
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	HCCA
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	HCCA
BP	GO:0033554	cellular response to stress	IEP	HCCA
CC	GO:0043227	membrane-bounded organelle	IEP	HCCA
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	HCCA
BP	GO:0050896	response to stimulus	IEP	HCCA
BP	GO:0051716	cellular response to stimulus	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR025834	TopoI_C_dom	948	1016
IPR013500	TopoI_cat_euk	688	912
IPR008336	TopoI_DNA-bd_euk	474	685

External Links

No external refs found!

Spa_g25841 (MGO1, TOP1, TOP1ALPHA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation