Aev_g14415 (ATMLH3, MLH3)

Aliases : ATMLH3, MLH3

Description : component *(MLH3) of MutLy endonuclease heterodimer & original description: none

Gene families : OG0004896 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0004896_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Aev_g14415

Target	Alias	Description	ECC score	Gene Family Method	Actions
Pir_g26529	ATMLH3, MLH3	component *(MLH3) of MutLy endonuclease heterodimer &...	0.02	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000287	magnesium ion binding	IEP	HCCA
MF	GO:0003824	catalytic activity	IEP	HCCA
MF	GO:0003924	GTPase activity	IEP	HCCA
MF	GO:0004743	pyruvate kinase activity	IEP	HCCA
MF	GO:0005515	protein binding	IEP	HCCA
MF	GO:0005525	GTP binding	IEP	HCCA
BP	GO:0005975	carbohydrate metabolic process	IEP	HCCA
BP	GO:0005984	disaccharide metabolic process	IEP	HCCA
BP	GO:0005985	sucrose metabolic process	IEP	HCCA
BP	GO:0005986	sucrose biosynthetic process	IEP	HCCA
BP	GO:0006082	organic acid metabolic process	IEP	HCCA
BP	GO:0006090	pyruvate metabolic process	IEP	HCCA
BP	GO:0006091	generation of precursor metabolites and energy	IEP	HCCA
BP	GO:0006096	glycolytic process	IEP	HCCA
BP	GO:0006163	purine nucleotide metabolic process	IEP	HCCA
BP	GO:0006165	nucleoside diphosphate phosphorylation	IEP	HCCA
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	HCCA
BP	GO:0006757	ATP generation from ADP	IEP	HCCA
BP	GO:0009056	catabolic process	IEP	HCCA
BP	GO:0009117	nucleotide metabolic process	IEP	HCCA
BP	GO:0009132	nucleoside diphosphate metabolic process	IEP	HCCA
BP	GO:0009135	purine nucleoside diphosphate metabolic process	IEP	HCCA
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	HCCA
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	HCCA
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	HCCA
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	IEP	HCCA
BP	GO:0009185	ribonucleoside diphosphate metabolic process	IEP	HCCA
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	HCCA
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	HCCA
BP	GO:0009259	ribonucleotide metabolic process	IEP	HCCA
BP	GO:0009311	oligosaccharide metabolic process	IEP	HCCA
BP	GO:0009312	oligosaccharide biosynthetic process	IEP	HCCA
BP	GO:0016051	carbohydrate biosynthetic process	IEP	HCCA
BP	GO:0016052	carbohydrate catabolic process	IEP	HCCA
MF	GO:0016787	hydrolase activity	IEP	HCCA
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	HCCA
MF	GO:0016791	phosphatase activity	IEP	HCCA
MF	GO:0017111	ribonucleoside triphosphate phosphatase activity	IEP	HCCA
MF	GO:0019001	guanyl nucleotide binding	IEP	HCCA
MF	GO:0019203	carbohydrate phosphatase activity	IEP	HCCA
BP	GO:0019637	organophosphate metabolic process	IEP	HCCA
BP	GO:0019693	ribose phosphate metabolic process	IEP	HCCA
BP	GO:0019752	carboxylic acid metabolic process	IEP	HCCA
MF	GO:0030955	potassium ion binding	IEP	HCCA
MF	GO:0031420	alkali metal ion binding	IEP	HCCA
MF	GO:0032561	guanyl ribonucleotide binding	IEP	HCCA
BP	GO:0032787	monocarboxylic acid metabolic process	IEP	HCCA
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	HCCA
MF	GO:0042578	phosphoric ester hydrolase activity	IEP	HCCA
BP	GO:0043436	oxoacid metabolic process	IEP	HCCA
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	HCCA
BP	GO:0046031	ADP metabolic process	IEP	HCCA
BP	GO:0046034	ATP metabolic process	IEP	HCCA
BP	GO:0046351	disaccharide biosynthetic process	IEP	HCCA
BP	GO:0046939	nucleotide phosphorylation	IEP	HCCA
MF	GO:0050307	sucrose-phosphate phosphatase activity	IEP	HCCA
MF	GO:0050308	sugar-phosphatase activity	IEP	HCCA
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	HCCA
BP	GO:0072521	purine-containing compound metabolic process	IEP	HCCA
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	HCCA
BP	GO:1901575	organic substance catabolic process	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR014790	MutL_C	1001	1163
IPR013507	DNA_mismatch_S5_2-like	216	275

External Links

No external refs found!

Aev_g14415 (ATMLH3, MLH3)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation