GSVIVT01026715001 (MLH1, ATMLH1)

Aliases : MLH1, ATMLH1

Description : DNA damage response.DNA repair mechanisms.mismatch repair (MMR).MLH1-PMS1 heterodimer.MLH1 component

Gene families : OG0003563 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0003563_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: GSVIVT01026715001

Target	Alias	Description	ECC score	Gene Family Method	Actions
Ppi_g13740	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.05	OrthoFinder output from all 47 species
Tin_g17142	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.02	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003924	GTPase activity	IEP	HCCA
MF	GO:0005525	GTP binding	IEP	HCCA
MF	GO:0016462	pyrophosphatase activity	IEP	HCCA
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	HCCA
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	HCCA
MF	GO:0017111	ribonucleoside triphosphate phosphatase activity	IEP	HCCA
MF	GO:0019001	guanyl nucleotide binding	IEP	HCCA
MF	GO:0032561	guanyl ribonucleotide binding	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR013507	DNA_mismatch_S5_2-like	226	347

External Links

No external refs found!

GSVIVT01026715001 (MLH1, ATMLH1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation