AT4G09140 (MLH1, ATMLH1)

Aliases : MLH1, ATMLH1

Description : MUTL-homologue 1

Gene families : OG0003563 (OrthoFinder output from all 47 species) Phylogenetic Tree(s): OG0003563_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT4G09140

Target	Alias	Description	ECC score	Gene Family Method
Adi_g018618	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.02	OrthoFinder output from all 47 species
Aev_g29114	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.02	OrthoFinder output from all 47 species
Ala_g12715	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.03	OrthoFinder output from all 47 species
Aop_g00761	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.02	OrthoFinder output from all 47 species
Ceric.05G021700.1	MLH1, ATMLH1,...	not classified & original description: pacid=50577530...	0.03	OrthoFinder output from all 47 species
Ceric.1Z069400.1	MLH1, ATMLH1,...	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.03	OrthoFinder output from all 47 species
Dac_g43000	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.02	OrthoFinder output from all 47 species
Dde_g00829	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.03	OrthoFinder output from all 47 species
LOC_Os01g72880.1	MLH1, ATMLH1,...	component MLH1 of MLH1-PMS1 heterodimer	0.03	OrthoFinder output from all 47 species
Sam_g24394	No alias	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.02	OrthoFinder output from all 47 species
Solyc04g045660.4.1	MLH1, ATMLH1,...	component MLH1 of MLH1-PMS1 heterodimer	0.04	OrthoFinder output from all 47 species
Tin_g17142	MLH1, ATMLH1	component *(MLH1) of MLH1-PMS1 heterodimer & original...	0.04	OrthoFinder output from all 47 species

Type	GO Term	Name	Evidence	Source
BP	GO:0000278	mitotic cell cycle	RCA	Interproscan
BP	GO:0000724	double-strand break repair via homologous recombination	RCA	Interproscan
BP	GO:0000725	recombinational repair	None	Extended
CC	GO:0000795	synaptonemal complex	IBA	Interproscan
BP	GO:0003006	developmental process involved in reproduction	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISM	Interproscan
CC	GO:0005712	chiasma	IBA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	None	Extended
BP	GO:0006261	DNA-templated DNA replication	RCA	Interproscan
BP	GO:0006275	regulation of DNA replication	RCA	Interproscan
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	ISS	Interproscan
BP	GO:0006298	mismatch repair	IBA	Interproscan
BP	GO:0006302	double-strand break repair	RCA	Interproscan
BP	GO:0006304	DNA modification	None	Extended
BP	GO:0006305	DNA alkylation	None	Extended
BP	GO:0006306	DNA methylation	RCA	Interproscan
BP	GO:0006310	DNA recombination	None	Extended
BP	GO:0006312	mitotic recombination	IMP	Interproscan
BP	GO:0006312	mitotic recombination	RCA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0007049	cell cycle	None	Extended
BP	GO:0007059	chromosome segregation	None	Extended
BP	GO:0007062	sister chromatid cohesion	RCA	Interproscan
BP	GO:0007129	homologous chromosome pairing at meiosis	RCA	Interproscan
BP	GO:0007131	reciprocal meiotic recombination	IBA	Interproscan
BP	GO:0007131	reciprocal meiotic recombination	RCA	Interproscan
BP	GO:0007275	multicellular organism development	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009555	pollen development	IMP	Interproscan
BP	GO:0009555	pollen development	RCA	Interproscan
BP	GO:0009560	embryo sac egg cell differentiation	RCA	Interproscan
BP	GO:0009719	response to endogenous stimulus	None	Extended
BP	GO:0009725	response to hormone	None	Extended
BP	GO:0009737	response to abscisic acid	RCA	Interproscan
BP	GO:0009790	embryo development	None	Extended
BP	GO:0009791	post-embryonic development	None	Extended
BP	GO:0009793	embryo development ending in seed dormancy	RCA	Interproscan
BP	GO:0009845	seed germination	IMP	Interproscan
BP	GO:0009845	seed germination	RCA	Interproscan
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010033	response to organic substance	None	Extended
BP	GO:0010154	fruit development	IMP	Interproscan
BP	GO:0010162	seed dormancy process	RCA	Interproscan
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010564	regulation of cell cycle process	RCA	Interproscan
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
BP	GO:0016444	somatic cell DNA recombination	RCA	Interproscan
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATP hydrolysis activity	IBA	Interproscan
MF	GO:0017111	ribonucleoside triphosphate phosphatase activity	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0022412	cellular process involved in reproduction in multicellular organism	None	Extended
BP	GO:0022414	reproductive process	None	Extended
BP	GO:0022611	dormancy process	None	Extended
BP	GO:0030154	cell differentiation	None	Extended
MF	GO:0030674	protein-macromolecule adaptor activity	ISS	Interproscan
MF	GO:0030983	mismatched DNA binding	IBA	Interproscan
BP	GO:0031047	RNA-mediated gene silencing	RCA	Interproscan
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0032259	methylation	None	Extended
CC	GO:0032300	mismatch repair complex	None	Extended
CC	GO:0032389	MutLalpha complex	IBA	Interproscan
CC	GO:0032390	MutLbeta complex	IBA	Interproscan
BP	GO:0032501	multicellular organismal process	None	Extended
BP	GO:0032502	developmental process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0033993	response to lipid	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0035825	homologous recombination	None	Extended
BP	GO:0042138	meiotic DNA double-strand break formation	RCA	Interproscan
BP	GO:0042221	response to chemical	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043414	macromolecule methylation	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044728	DNA methylation or demethylation	None	Extended
BP	GO:0045132	meiotic chromosome segregation	RCA	Interproscan
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0048229	gametophyte development	None	Extended
BP	GO:0048316	seed development	IMP	Interproscan
BP	GO:0048366	leaf development	RCA	Interproscan
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048608	reproductive structure development	None	Extended
BP	GO:0048609	multicellular organismal reproductive process	None	Extended
BP	GO:0048825	cotyledon development	RCA	Interproscan
BP	GO:0048827	phyllome development	None	Extended
BP	GO:0048856	anatomical structure development	None	Extended
BP	GO:0048869	cellular developmental process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0051726	regulation of cell cycle	RCA	Interproscan
MF	GO:0060090	molecular adaptor activity	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0061982	meiosis I cell cycle process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0070192	chromosome organization involved in meiotic cell cycle	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:0097305	response to alcohol	None	Extended
BP	GO:0098813	nuclear chromosome segregation	None	Extended
CC	GO:0099086	synaptonemal structure	None	Extended
BP	GO:0099402	plant organ development	None	Extended
CC	GO:0110165	cellular anatomical entity	None	Extended
CC	GO:0140513	nuclear protein-containing complex	None	Extended
BP	GO:0140527	reciprocal homologous recombination	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901700	response to oxygen-containing compound	None	Extended
BP	GO:1903046	meiotic cell cycle process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000502	proteasome complex	IEP	HCCA
MF	GO:0003747	translation release factor activity	IEP	HCCA
MF	GO:0004518	nuclease activity	IEP	HCCA
MF	GO:0004527	exonuclease activity	IEP	HCCA
CC	GO:0005622	intracellular anatomical structure	IEP	HCCA
BP	GO:0006415	translational termination	IEP	HCCA
MF	GO:0008079	translation termination factor activity	IEP	HCCA
MF	GO:0008135	translation factor activity, RNA binding	IEP	HCCA
MF	GO:0008408	3'-5' exonuclease activity	IEP	HCCA
BP	GO:0009756	carbohydrate mediated signaling	IEP	HCCA
BP	GO:0009933	meristem structural organization	IEP	HCCA
BP	GO:0010182	sugar mediated signaling pathway	IEP	HCCA
BP	GO:0016567	protein ubiquitination	IEP	HCCA
BP	GO:0019915	lipid storage	IEP	HCCA
BP	GO:0022411	cellular component disassembly	IEP	HCCA
BP	GO:0030243	cellulose metabolic process	IEP	HCCA
BP	GO:0030244	cellulose biosynthetic process	IEP	HCCA
BP	GO:0032984	protein-containing complex disassembly	IEP	HCCA
MF	GO:0045182	translation regulator activity	IEP	HCCA
BP	GO:0048481	plant ovule development	IEP	HCCA
BP	GO:0048532	anatomical structure arrangement	IEP	HCCA
BP	GO:0050826	response to freezing	IEP	HCCA
BP	GO:0051235	maintenance of location	IEP	HCCA
BP	GO:0051273	beta-glucan metabolic process	IEP	HCCA
BP	GO:0051274	beta-glucan biosynthetic process	IEP	HCCA
BP	GO:0051301	cell division	IEP	HCCA
MF	GO:0090079	translation regulator activity, nucleic acid binding	IEP	HCCA
CC	GO:1905368	peptidase complex	IEP	HCCA
CC	GO:1905369	endopeptidase complex	IEP	HCCA

InterPro domains	Description	Start	Stop
IPR013507	DNA_mismatch_S5_2-like	237	356
IPR032189	Mlh1_C	454	737

External Links

No external refs found!

AT4G09140 (MLH1, ATMLH1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation