MA_585937g0010


Description : 26.17 misc.dynamin At3g60190 encodes Arabidopsis dynamin-related protein 1E, DRP1E, also known as EDR3, ADL4 and ADL1E, which is 624 amino acid residues long, has a predicted mass of 69.8 kDa and a pI of 7.5. Dynamin-related protein 1E belongs to a plant-specific subclass of dynamin-related proteins (DRP1), consisting of five members in Arabidopsis (A, B, C, D, E). This class is characterized by having an N-terminal GTPase domain, a central ëdynamin 2ë domain and a C-terminal GTPase effector domain (GED), a typical structure for plant dynamin-related proteins. However, this class lacks a PH domain and a proline-rich domain, which are found in classical animal dynamin-like proteins. Based on work on animal dynamins, the plant DRP1 proteins should be able to form polymeric structures that wrap around membranes to facilitate membrane tubulation and pinching off of vesicles, processes that are essential to vesicle trafficking and membrane compartmentalization. The edr3 mutation causes a P77L substitution in the G2 motif of the GTPase domain of DRP1E. edr3 mutant Arabidopsis plants display enhanced cell death in response to powdery mildew infection. DYNAMIN-like 1E (DL1E)


Gene families : OG_01_0000799 (Gene family) Phylogenetic Tree(s): OG0000799_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR network (cutoff 100): MA_585937g0010
Cluster HCCA cluster: Cluster_462

Target Alias Description ECC score Gene Family Method Actions
AT1G14830 DRP1C, ADL1C, DL1C, ADL5 DYNAMIN-like 1C 0.02 Gene family
GSVIVT01018380001 No alias 26.17 misc.dynamin At3g60190 encodes Arabidopsis... 0.04 Gene family
LOC_Os05g48240 Os05g0556100 30.5 signalling.G-proteins Encodes a dynamin-like... 0.02 Gene family
Solyc05g050600.3.1 Solyc05g050600.3 30.5 signalling.G-proteins Encodes a dynamin-like... 0.05 Gene family
Zm00001d009504 GRMZM2G314647 30.5 signalling.G-proteins Encodes a dynamin-like... 0.02 Gene family
Zm00001d033751 GRMZM2G126019 26.17 misc.dynamin Encodes a dynamin-like protein that... 0.02 Gene family
Zm00001d038955 GRMZM2G149717 30.5 signalling.G-proteins Encodes a dynamin-like... 0.04 Gene family

Type GO Term Name Evidence Source
MF GO:0005525 GTP binding IEA InterProScan
Type GO Term Name Evidence Source

No Predicted GO terms available for this sequence

InterPro domains Description Start Stop
IPR000375 Dynamin_central 52 269
IPR022812 Dynamin_SF 1 42
No external refs found!