GO:0007186: G-protein coupled receptor signaling pathway (Biological process)

"A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576)." [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]


There are 92 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_281 Oryza sativa 0.78 % 0.00351 0.022011
Cluster_398 Picea abies 1.27 % 0.000215 0.006748
Cluster_422 Picea abies 1.82 % 0.007703 0.029236
Cluster_264 Picea abies 1.1 % 0.000286 0.004353
Sequences (92) (download table)

InterPro Domains

GO Terms

Family Terms