GO:0007187: G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (Biological process)

"The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide." [GOC:mah, GOC:signaling, ISBN:0815316194]


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