GO:0007186: G protein-coupled receptor signaling pathway (Biological process)

"A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane." [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]


There are 137 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_299 Gingko biloba 5.45 % 0.0 1.1e-05
Cluster_83 Marchantia polymorpha 1.45 % 0.000738 0.005356
Cluster_58 Physcomitrella patens 1.67 % 0.001849 0.018794
Cluster_284 Picea abies 1.45 % 0.010308 0.045527
Cluster_268 Picea abies 1.54 % 0.000168 0.007122
Cluster_283 Solanum lycopersicum 3.51 % 0.000368 0.03863
Sequences (137) (download table)

InterPro Domains

GO Terms

Family Terms