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GO:0007186: G protein-coupled receptor signaling pathway (Biological process)

"The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane." [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]


There are 7779 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_328 Gingko biloba 4.23 % 1e-06 3.3e-05
Cluster_174 Oryza sativa 1.2 % 0.001802 0.010512
Cluster_96 Physcomitrella patens 1.82 % 0.001695 0.020052
Cluster_254 Solanum lycopersicum 0.98 % 0.004572 0.033146
Cluster_507 Picea abies 1.52 % 0.009862 0.030793
Cluster_453 Picea abies 1.85 % 0.000116 0.005691
Cluster_109 Alsophila latebrosa 2.44 % 0.000333 0.007261
Cluster_29 Alsophila latebrosa 1.87 % 0.000565 0.009364
Cluster_214 Amblovenatum opulentum 1.12 % 0.003877 0.049574
Cluster_948 Amblovenatum opulentum 33.33 % 0.001552 0.005277
Cluster_123 Amblovenatum opulentum 1.03 % 0.004584 0.023084
Cluster_398 Angiopteris evecta 1.16 % 0.018798 0.049725
Cluster_181 Lindsaea ensifolia 0.22 % 0.002154 0.019355
Cluster_510 Lindsaea ensifolia 1.52 % 0.013115 0.047542
Cluster_339 Microlepia speluncae 1.79 % 0.007981 0.027228
Cluster_460 Microlepia speluncae 1.39 % 0.010251 0.037928
Cluster_85 Pleocnemia irregularis 1.79 % 0.023227 0.048531
Cluster_177 Salvinia molesta 3.64 % 0.000159 0.01861
Cluster_579 Salvinia molesta 3.92 % 0.000137 0.004989
Cluster_236 Diplazium proliferum (Lam.) Kaulf. 1.37 % 0.014047 0.045178
Cluster_825 Pyrrosia piloselloides 50.0 % 0.0009 0.003798
Cluster_312 Ophioglossum reticulatum 2.17 % 0.000179 0.009908
Cluster_224 Ophioglossum reticulatum 3.45 % 7.1e-05 0.007738
Cluster_60 Stenochlaena palustris 2.0 % 0.012115 0.042179
Cluster_402 Stenochlaena palustris 2.53 % 0.000168 0.013275
Cluster_410 Dicranopteris curranii 1.45 % 0.015822 0.049726
Cluster_512 Dicranopteris curranii 4.55 % 4.6e-05 0.004463
Sequences (7779) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !