GO:0005852: eukaryotic translation initiation factor 3 complex (Cellular component)

"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]


There are 56 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_171 Arabidopsis thaliana 2.5 % 7e-06 0.000436
Cluster_45 Cyanophora paradoxa 0.83 % 0.000557 0.002727
Cluster_64 Chlamydomonas reinhardtii 2.8 % 1e-06 1.6e-05
Cluster_256 Oryza sativa 1.67 % 0.008977 0.02641
Cluster_67 Oryza sativa 0.77 % 0.000617 0.003467
Cluster_68 Picea abies 0.8 % 0.000662 0.04728
Cluster_165 Solanum lycopersicum 0.84 % 0.000683 0.003658
Cluster_121 Solanum lycopersicum 1.23 % 0.000318 0.005106
Cluster_85 Vitis vinifera 1.56 % 0.000232 0.004408
Cluster_120 Zea mays 3.95 % 1e-06 4e-06
Cluster_331 Zea mays 2.04 % 0.012495 0.03865
Cluster_345 Zea mays 2.27 % 0.011226 0.036239
Sequences (56) (download table)

InterPro Domains

GO Terms

Family Terms