GO:0005852: eukaryotic translation initiation factor 3 complex (Cellular component)

"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]


There are 5101 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_244 Amborella trichopoda 2.33 % 9.7e-05 0.00599
Cluster_202 Arabidopsis thaliana 6.82 % 0.0 1.1e-05
Cluster_81 Chlamydomonas reinhardtii 7.55 % 0.0 0.0
Cluster_18 Cyanophora paradoxa 1.47 % 0.010967 0.029539
Cluster_13 Cyanophora paradoxa 1.7 % 1e-06 7.5e-05
Cluster_330 Gingko biloba 1.43 % 0.013477 0.042176
Cluster_85 Marchantia polymorpha 1.89 % 0.013572 0.044245
Cluster_305 Oryza sativa 2.78 % 4.3e-05 0.000181
Cluster_272 Oryza sativa 1.82 % 0.007797 0.029239
Cluster_242 Physcomitrella patens 2.04 % 0.009024 0.015116
Cluster_120 Physcomitrella patens 3.41 % 0.0 2.3e-05
Cluster_248 Solanum lycopersicum 1.72 % 0.011855 0.032539
Cluster_19 Solanum lycopersicum 0.81 % 0.001073 0.006477
Cluster_30 Vitis vinifera 0.86 % 0.000765 0.003364
Cluster_71 Zea mays 1.55 % 0.000339 0.001017
Cluster_59 Zea mays 1.53 % 0.00035 0.001754
Cluster_489 Picea abies 1.69 % 0.00882 0.02932
Cluster_256 Picea abies 0.79 % 0.018898 0.046986
Cluster_517 Picea abies 1.35 % 0.011051 0.046354
Cluster_301 Abrodictyum obscurum 1.79 % 0.006442 0.03427
Cluster_296 Abrodictyum obscurum 0.74 % 0.015587 0.045102
Cluster_330 Adiantum latifolium 1.79 % 0.008452 0.047028
Cluster_427 Adiantum latifolium 2.22 % 0.006797 0.0438
Cluster_250 Adiantum latifolium 0.84 % 0.017889 0.048025
Cluster_211 Alsophila latebrosa 1.3 % 0.01192 0.041958
Cluster_395 Alsophila latebrosa 1.6 % 0.000167 0.02107
Cluster_651 Amblovenatum opulentum 2.67 % 7.1e-05 0.01132
Cluster_6 Amblovenatum opulentum 1.43 % 0.011688 0.040074
Cluster_172 Amblovenatum opulentum 1.46 % 5e-06 6.6e-05
Cluster_460 Angiopteris evecta 1.11 % 0.012559 0.049202
Cluster_48 Davallia denticulata 1.05 % 0.014356 0.031105
Cluster_248 Davallia denticulata 1.18 % 0.012853 0.037942
Cluster_738 Lindsaea ensifolia 33.33 % 0.00035 0.004897
Cluster_521 Lindsaea ensifolia 2.08 % 0.005584 0.028413
Cluster_271 Microlepia speluncae 1.45 % 0.005626 0.035044
Cluster_424 Microlepia speluncae 1.43 % 0.005708 0.042658
Cluster_12 Nephrolepis biserrata 0.91 % 0.000234 0.003796
Cluster_111 Nephrolepis biserrata 1.89 % 0.005855 0.024882
Cluster_633 Pleocnemia irregularis 33.33 % 0.000719 0.01186
Cluster_70 Pleocnemia irregularis 1.1 % 0.000865 0.01994
Cluster_251 Salvinia molesta 1.85 % 0.000422 0.002052
Cluster_128 Salvinia molesta 1.61 % 0.017352 0.049857
Cluster_467 Salvinia molesta 2.22 % 0.000293 0.03505
Cluster_51 Tectaria incisa 1.04 % 0.012308 0.024908
Cluster_329 Diplazium proliferum (Lam.) Kaulf. 2.5 % 2.9e-05 0.001101
Cluster_297 Diplazium proliferum (Lam.) Kaulf. 1.3 % 0.008256 0.035499
Cluster_227 Pyrrosia piloselloides 1.35 % 0.006868 0.039165
Cluster_352 Pyrrosia piloselloides 0.84 % 0.011025 0.046754
Cluster_137 Ophioglossum reticulatum 0.96 % 0.000908 0.003822
Cluster_373 Stenochlaena palustris 1.52 % 0.011428 0.029298
Cluster_441 Stenochlaena palustris 2.27 % 0.007632 0.036832
Cluster_137 Stenochlaena palustris 1.38 % 6e-06 0.00011
Cluster_447 Stenochlaena palustris 1.89 % 0.009186 0.032473
Cluster_220 Dicranopteris curranii 0.94 % 0.014195 0.036388
Cluster_76 Dicranopteris curranii 0.65 % 0.020698 0.046715
Cluster_197 Alsophila spinulosa 0.81 % 0.013794 0.030951
Cluster_166 Lygodium flexuosum 1.19 % 0.012141 0.043415
Cluster_108 Lygodium flexuosum 1.64 % 0.008829 0.028752
Sequences (5101) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !