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GO:0004420: hydroxymethylglutaryl-CoA reductase (NADPH) activity (Molecular function)

"Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH." [EC:1.1.1.34, RHEA:15989]


There are 51 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_4 Amborella trichopoda 0.7 % 0.005199 0.016434
Cluster_69 Gingko biloba 2.08 % 1e-06 8e-06
Cluster_46 Gingko biloba 3.39 % 0.000302 0.001656
Cluster_162 Marchantia polymorpha 1.03 % 0.004995 0.043179
Cluster_302 Oryza sativa 1.02 % 0.006953 0.047278
Cluster_420 Picea abies 2.86 % 0.000165 0.011196
Cluster_41 Picea abies 1.52 % 2e-05 0.000235
Cluster_652 Picea abies 50.0 % 0.00054 0.019988
Cluster_519 Picea abies 3.33 % 0.000121 0.008259
Cluster_618 Zea mays 50.0 % 0.000144 0.005339
Sequences (51) (download table)

InterPro Domains

GO Terms

Family Terms