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GO:0004222: metalloendopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions." [GOC:mah, http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE, http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE]


There are 206 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_192 Arabidopsis thaliana 2.2 % 0.003632 0.010412
Cluster_37 Arabidopsis thaliana 1.5 % 0.007591 0.045006
Cluster_54 Cyanophora paradoxa 2.02 % 0.002882 0.043645
Cluster_8 Oryza sativa 1.36 % 0.00031 0.007416
Cluster_223 Oryza sativa 0.87 % 0.008447 0.029021
Cluster_205 Picea abies 3.35 % 0.0 0.0
Cluster_1095 Picea abies 50.0 % 0.001124 0.010116
Cluster_231 Picea abies 2.0 % 0.001473 0.011005
Cluster_17 Solanum lycopersicum 1.43 % 0.003195 0.029242
Cluster_303 Solanum lycopersicum 2.99 % 0.000746 0.02194
Cluster_148 Vitis vinifera 1.75 % 0.004813 0.028618
Cluster_126 Vitis vinifera 4.76 % 2.5e-05 0.004377
Cluster_246 Zea mays 1.17 % 0.00767 0.037162
Cluster_233 Zea mays 3.23 % 0.001051 0.004861
Sequences (206) (download table)

InterPro Domains

GO Terms

Family Terms