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GO:0004252: serine-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]


There are 912 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_7 Amborella trichopoda 9.24 % 0.0 0.0
Cluster_145 Arabidopsis thaliana 3.03 % 0.000337 0.004233
Cluster_18 Chlamydomonas reinhardtii 2.8 % 0.000598 0.034385
Cluster_135 Cyanophora paradoxa 4.92 % 0.000955 0.014093
Cluster_79 Cyanophora paradoxa 4.94 % 0.000127 0.018198
Cluster_97 Cyanophora paradoxa 4.84 % 0.001002 0.007108
Cluster_507 Gingko biloba 100.0 % 3e-06 5.4e-05
Cluster_86 Gingko biloba 5.0 % 1.2e-05 8.4e-05
Cluster_97 Gingko biloba 5.56 % 0.000118 0.015122
Cluster_250 Marchantia polymorpha 50.0 % 0.002984 0.037304
Cluster_129 Oryza sativa 3.75 % 0.000541 0.033528
Cluster_87 Oryza sativa 3.57 % 0.000624 0.029102
Cluster_239 Oryza sativa 2.0 % 0.003287 0.038353
Cluster_215 Oryza sativa 1.76 % 0.001075 0.033698
Cluster_42 Oryza sativa 1.43 % 0.00834 0.024342
Cluster_112 Oryza sativa 2.6 % 0.010169 0.035388
Cluster_262 Physcomitrella patens 1.64 % 0.000618 0.004263
Cluster_458 Picea abies 3.17 % 0.004939 0.020373
Cluster_296 Picea abies 4.23 % 0.000231 0.002177
Cluster_704 Picea abies 14.29 % 0.011499 0.026065
Cluster_65 Picea abies 2.1 % 0.001766 0.013633
Cluster_431 Picea abies 3.09 % 0.000576 0.030266
Cluster_511 Picea abies 5.8 % 6e-06 0.000845
Cluster_24 Picea abies 2.03 % 0.000335 0.002664
Cluster_119 Picea abies 2.26 % 0.001436 0.017558
Cluster_220 Picea abies 4.41 % 0.000203 0.001792
Cluster_622 Picea abies 100.0 % 3e-06 4.9e-05
Cluster_88 Picea abies 2.99 % 9e-06 5.1e-05
Cluster_148 Selaginella moellendorffii 2.33 % 0.002947 0.03242
Cluster_328 Selaginella moellendorffii 50.0 % 0.001884 0.005651
Cluster_100 Solanum lycopersicum 1.79 % 0.006494 0.021457
Cluster_12 Solanum lycopersicum 2.12 % 0.001123 0.031065
Cluster_86 Solanum lycopersicum 6.74 % 1e-06 8.7e-05
Cluster_77 Solanum lycopersicum 5.71 % 1e-06 7.5e-05
Cluster_143 Solanum lycopersicum 4.76 % 0.000174 0.004113
Cluster_33 Vitis vinifera 4.05 % 4e-06 0.000938
Cluster_476 Vitis vinifera 50.0 % 0.007577 0.037885
Cluster_80 Vitis vinifera 3.85 % 0.01672 0.041635
Cluster_372 Vitis vinifera 25.0 % 0.015097 0.04618
Cluster_25 Zea mays 1.63 % 0.001154 0.041539
Cluster_143 Zea mays 1.86 % 0.0007 0.00198
Sequences (912) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms