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GO:0004252: serine-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]


There are 21060 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_593 Actinostachys digitata 50.0 % 0.001719 0.030939
Cluster_232 Actinostachys digitata 2.86 % 0.001703 0.037275
Cluster_172 Actinostachys digitata 2.47 % 0.002271 0.020814
Cluster_95 Angiopteris evecta 1.38 % 0.001108 0.006883
Cluster_148 Amblovenatum opulentum 3.26 % 7e-05 0.001006
Cluster_58 Alsophila spinulosa 1.31 % 0.004812 0.024917
Cluster_28 Amborella trichopoda 7.48 % 0.0 0.0
Cluster_74 Amborella trichopoda 10.1 % 0.0 0.0
Cluster_77 Chlamydomonas reinhardtii 4.55 % 0.006307 0.010551
Cluster_27 Chlamydomonas reinhardtii 3.17 % 0.000371 0.038174
Cluster_167 Diplazium proliferum (Lam.) Kaulf. 2.4 % 0.000107 0.0101
Cluster_516 Dicranopteris curranii 50.0 % 0.001808 0.032551
Cluster_511 Dicranopteris curranii 2.4 % 0.000204 0.007905
Cluster_414 Dicranopteris curranii 50.0 % 0.001808 0.041593
Cluster_41 Equisetum hyemale 1.12 % 0.010327 0.043951
Cluster_126 Ginkgo biloba 4.26 % 0.003078 0.040017
Cluster_100 Ginkgo biloba 6.78 % 4e-06 2.6e-05
Cluster_327 Ginkgo biloba 100.0 % 3e-06 5.4e-05
Cluster_109 Lindsaea ensifolia 2.19 % 0.000125 0.007295
Cluster_30 Lygodium flexuosum 3.64 % 0.000739 0.027113
Cluster_79 Microlepia speluncae 1.07 % 0.005506 0.02225
Cluster_17 Microlepia speluncae 1.09 % 0.00528 0.032352
Cluster_8 Marchantia polymorpha 3.77 % 0.00283 0.012358
Cluster_139 Marchantia polymorpha 50.0 % 0.002984 0.037304
Cluster_30 Marchantia polymorpha 1.74 % 0.012715 0.044605
Cluster_154 Nephrolepis biserrata 1.77 % 0.003115 0.037154
Cluster_68 Oryza sativa 6.12 % 0.000127 0.001821
Cluster_48 Oryza sativa 2.59 % 0.001586 0.008178
Cluster_135 Oryza sativa 4.55 % 0.003428 0.016479
Cluster_81 Oryza sativa 4.55 % 3e-06 0.000521
Cluster_84 Oryza sativa 2.74 % 0.00918 0.046787
Cluster_422 Picea abies 14.29 % 0.011499 0.026065
Cluster_253 Picea abies 11.36 % 0.0 1e-06
Cluster_340 Picea abies 100.0 % 3e-06 4.9e-05
Cluster_246 Picea abies 4.26 % 0.002781 0.022463
Cluster_134 Picea abies 3.33 % 0.004491 0.017962
Cluster_169 Picea abies 2.02 % 0.011804 0.025722
Cluster_349 Pleocnemia irregularis 50.0 % 0.001557 0.018686
Cluster_6 Psilotum nudum 1.61 % 0.001931 0.025378
Cluster_160 Pyrrosia piloselloides 1.18 % 0.006913 0.034566
Cluster_236 Pyrrosia piloselloides 2.25 % 0.001957 0.017609
Cluster_361 Pyrrosia piloselloides 50.0 % 0.001458 0.026237
Cluster_209 Salvinia molesta 25.0 % 0.009521 0.013647
Cluster_60 Salvinia molesta 10.14 % 0.0 0.0
Cluster_28 Salvinia molesta 3.7 % 0.000137 0.001014
Cluster_50 Salvinia molesta 5.32 % 3e-06 0.000231
Cluster_81 Salvinia molesta 2.62 % 0.000101 0.002019
Cluster_46 Salvinia molesta 10.56 % 0.0 0.0
Cluster_93 Salvinia molesta 5.6 % 0.0 0.0
Cluster_115 Solanum lycopersicum 12.24 % 0.0 0.0
Cluster_113 Solanum lycopersicum 8.33 % 1.9e-05 0.000289
Cluster_218 Selaginella moellendorffii 50.0 % 0.001884 0.005651
Cluster_95 Stenochlaena palustris 2.02 % 5.4e-05 0.000519
Cluster_47 Tectaria incisa 2.35 % 0.001779 0.026385
Cluster_20 Vitis vinifera 4.51 % 1.2e-05 0.001111
Cluster_350 Vitis vinifera 50.0 % 0.007577 0.045462
Cluster_246 Vitis vinifera 25.0 % 0.015097 0.04618
Cluster_73 Vitis vinifera 3.33 % 0.004909 0.045404
Cluster_71 Zea mays 1.71 % 0.020026 0.03418
Cluster_51 Zea mays 2.88 % 0.000972 0.006876
Cluster_140 Arabidopsis thaliana 4.65 % 0.005186 0.04702
Sequences (21060) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !