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GO:0004190: aspartic-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile." [ISBN:0198506732]


There are 6422 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_397 Actinostachys digitata 1.05 % 0.00129 0.021257
Cluster_182 Alsophila spinulosa 10.0 % 0.005443 0.022451
Cluster_76 Amborella trichopoda 12.2 % 0.0 1e-06
Cluster_73 Amborella trichopoda 7.27 % 5e-06 0.000344
Cluster_49 Amborella trichopoda 2.26 % 0.000515 0.004255
Cluster_40 Cibotium barometz 1.35 % 0.016707 0.045524
Cluster_255 Cibotium barometz 3.64 % 7.2e-05 0.003858
Cluster_1 Chlamydomonas reinhardtii 1.72 % 0.016242 0.044858
Cluster_35 Dicranopteris curranii 2.38 % 0.007252 0.01744
Cluster_156 Lindsaea ensifolia 2.17 % 0.009917 0.042217
Cluster_208 Lygodium flexuosum 50.0 % 0.000678 0.005761
Cluster_56 Lygodium flexuosum 1.52 % 3.8e-05 0.004388
Cluster_17 Microlepia speluncae 1.64 % 3e-06 0.000103
Cluster_356 Pleocnemia irregularis 50.0 % 0.000719 0.009704
Cluster_225 Pleocnemia irregularis 4.55 % 0.000116 0.009171
Cluster_166 Pyrrosia piloselloides 1.2 % 0.011529 0.034037
Cluster_90 Selaginella moellendorffii 1.47 % 0.015165 0.041452
Cluster_103 Zea mays 1.47 % 0.017847 0.035694
Sequences (6422) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !