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GO:0004190: aspartic-type endopeptidase activity (Molecular function)

"Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile." [ISBN:0198506732]


There are 6422 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_76 Amborella trichopoda 9.09 % 0.0 5e-06
Cluster_49 Amborella trichopoda 1.97 % 0.00086 0.005848
Cluster_73 Amborella trichopoda 6.9 % 7e-06 0.000432
Cluster_179 Gingko biloba 0.72 % 0.001575 0.032056
Cluster_305 Oryza sativa 1.39 % 0.016937 0.027506
Cluster_328 Oryza sativa 2.13 % 0.011086 0.041295
Cluster_269 Oryza sativa 1.35 % 1.7e-05 0.003539
Cluster_320 Oryza sativa 1.33 % 0.017638 0.036697
Cluster_176 Selaginella moellendorffii 1.89 % 0.011836 0.039947
Cluster_90 Selaginella moellendorffii 1.33 % 0.016716 0.046062
Cluster_230 Solanum lycopersicum 2.35 % 0.000219 0.00255
Cluster_43 Vitis vinifera 1.04 % 0.001083 0.017843
Cluster_291 Zea mays 1.47 % 0.017847 0.045519
Cluster_356 Zea mays 2.04 % 0.01289 0.021586
Cluster_137 Zea mays 0.81 % 0.001866 0.009928
Cluster_103 Zea mays 1.12 % 0.0233 0.043173
Cluster_286 Picea abies 2.0 % 0.000416 0.010198
Cluster_482 Picea abies 1.82 % 0.016382 0.043003
Cluster_266 Picea abies 1.14 % 0.001263 0.005627
Cluster_346 Picea abies 1.85 % 0.016087 0.034971
Cluster_427 Picea abies 2.04 % 0.0004 0.013261
Cluster_317 Abrodictyum obscurum 1.19 % 0.00096 0.017559
Cluster_660 Alsophila latebrosa 2.38 % 0.000111 0.004807
Cluster_604 Amblovenatum opulentum 1.96 % 0.01206 0.043798
Cluster_465 Amblovenatum opulentum 2.44 % 0.000175 0.009177
Cluster_423 Angiopteris evecta 0.61 % 0.022646 0.04814
Cluster_470 Angiopteris evecta 0.82 % 0.016991 0.039572
Cluster_224 Angiopteris evecta 2.25 % 6.6e-05 0.003908
Cluster_284 Davallia denticulata 1.49 % 0.012664 0.036522
Cluster_200 Davallia denticulata 1.56 % 0.0121 0.032098
Cluster_273 Equisetum hyemale 3.51 % 0.000166 0.002615
Cluster_17 Microlepia speluncae 1.26 % 6e-06 0.000213
Cluster_277 Nephrolepis biserrata 0.91 % 0.001262 0.007593
Cluster_700 Pleocnemia irregularis 50.0 % 0.000719 0.009704
Cluster_225 Pleocnemia irregularis 2.67 % 0.000338 0.038218
Cluster_388 Tectaria incisa 1.64 % 0.010434 0.030385
Cluster_121 Tectaria incisa 1.28 % 0.013324 0.04711
Cluster_307 Pyrrosia piloselloides 1.72 % 0.008069 0.049453
Cluster_166 Pyrrosia piloselloides 1.14 % 0.012219 0.035221
Cluster_384 Pyrrosia piloselloides 1.09 % 0.012772 0.047184
Cluster_234 Pyrrosia piloselloides 1.41 % 0.009869 0.027011
Cluster_511 Dicranopteris curranii 1.79 % 0.009659 0.036826
Cluster_35 Dicranopteris curranii 1.89 % 0.009144 0.027813
Cluster_272 Alsophila spinulosa 3.28 % 0.00052 0.006078
Cluster_468 Alsophila spinulosa 10.0 % 0.005443 0.022451
Cluster_479 Lygodium flexuosum 50.0 % 0.000678 0.005761
Cluster_56 Lygodium flexuosum 0.92 % 0.000168 0.013589
Sequences (6422) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !