GO:0003918: DNA topoisomerase type II (ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192]


There are 50 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_199 Arabidopsis thaliana 1.85 % 0.017612 0.038263
Cluster_40 Cyanophora paradoxa 1.4 % 1.3e-05 9.7e-05
Cluster_126 Cyanophora paradoxa 1.67 % 0.014487 0.047918
Cluster_2 Oryza sativa 1.27 % 0.007886 0.040115
Cluster_375 Picea abies 1.52 % 0.008317 0.02614
Cluster_87 Picea abies 1.89 % 7.9e-05 0.000351
Cluster_302 Solanum lycopersicum 1.49 % 0.007662 0.026568
Cluster_176 Solanum lycopersicum 1.79 % 0.006407 0.029899
Cluster_92 Vitis vinifera 1.2 % 0.012543 0.041809
Cluster_156 Zea mays 1.28 % 0.009961 0.022903
Cluster_188 Zea mays 1.19 % 0.010724 0.048256
Sequences (50) (download table)

InterPro Domains

GO Terms

Family Terms