GO:0003713: transcription coactivator activity (Molecular function)

"A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator." [GOC:txnOH-2018, PMID:10213677, PMID:16858867]


There are 50 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_47 Oryza sativa 1.19 % 0.008383 0.037725
Cluster_81 Picea abies 0.89 % 0.003145 0.030581
Cluster_272 Solanum lycopersicum 1.67 % 0.008572 0.029311
Sequences (50) (download table)

InterPro Domains

GO Terms

Family Terms