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GO:0003712: transcription coregulator activity (Molecular function)

"A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator]


There are 192 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_127 Arabidopsis thaliana 1.98 % 0.005125 0.0183
Cluster_48 Arabidopsis thaliana 1.94 % 0.005325 0.020465
Cluster_376 Oryza sativa 50.0 % 0.001301 0.013878
Cluster_106 Oryza sativa 1.18 % 0.005407 0.017245
Cluster_148 Oryza sativa 2.44 % 4e-06 4.5e-05
Cluster_26 Oryza sativa 1.39 % 0.00037 0.018801
Cluster_76 Picea abies 2.08 % 0.012074 0.023142
Cluster_309 Solanum lycopersicum 3.39 % 0.001524 0.028754
Cluster_37 Solanum lycopersicum 2.54 % 1e-06 0.000171
Cluster_292 Vitis vinifera 50.0 % 0.001594 0.014342
Cluster_208 Zea mays 4.0 % 0.000685 0.034697
Cluster_271 Zea mays 2.41 % 0.001873 0.04307
Cluster_555 Zea mays 50.0 % 0.001538 0.016404
Cluster_344 Zea mays 6.0 % 8e-06 0.000376
Sequences (192) (download table)

InterPro Domains

GO Terms

Family Terms