1. Home
  2. GO
  3. GO:0003712

GO:0003712: transcription coregulator activity (Molecular function)

"A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator]


There are 280 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_254 Amborella trichopoda 3.51 % 0.000383 0.003661
Cluster_225 Arabidopsis thaliana 2.17 % 0.004482 0.045753
Cluster_43 Arabidopsis thaliana 1.51 % 0.001291 0.004483
Cluster_129 Chlamydomonas reinhardtii 1.53 % 0.00035 0.033135
Cluster_199 Gingko biloba 3.53 % 1.9e-05 0.001516
Cluster_129 Gingko biloba 3.85 % 1.4e-05 0.002819
Cluster_60 Marchantia polymorpha 1.32 % 0.001571 0.007815
Cluster_361 Oryza sativa 2.41 % 0.0015 0.008686
Cluster_183 Oryza sativa 1.6 % 0.003355 0.026618
Cluster_252 Physcomitrella patens 1.85 % 0.018152 0.041804
Cluster_218 Picea abies 1.64 % 0.019951 0.047098
Cluster_1377 Picea abies 50.0 % 0.00066 0.001651
Cluster_17 Selaginella moellendorffii 1.08 % 0.001006 0.021249
Cluster_33 Solanum lycopersicum 1.3 % 0.003107 0.03211
Cluster_196 Solanum lycopersicum 2.27 % 0.005559 0.042821
Cluster_286 Vitis vinifera 50.0 % 0.001594 0.014873
Cluster_173 Vitis vinifera 2.38 % 0.000133 0.03081
Cluster_28 Zea mays 2.6 % 0.0 2e-06
Cluster_145 Zea mays 1.67 % 0.003637 0.045894
Sequences (280) (download table)

InterPro Domains

GO Terms

Family Terms