GO:0003713: transcription coactivator activity (Molecular function)

"A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator." [GOC:txnOH-2018, PMID:10213677, PMID:16858867]

There are 1227 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_229 Actinostachys digitata 0.77 % 0.003986 0.043465
Cluster_116 Amblovenatum opulentum 2.08 % 0.002013 0.012078
Cluster_85 Amborella trichopoda 0.51 % 0.014446 0.041667
Cluster_98 Ginkgo biloba 1.39 % 0.00522 0.034724
Cluster_26 Oryza sativa 1.35 % 0.006998 0.026774
Cluster_1095 Picea abies 50.0 % 6e-05 0.00024
Cluster_58 Solanum lycopersicum 2.27 % 0.00644 0.026834
Cluster_181 Tectaria incisa 0.8 % 0.002685 0.017427
Cluster_85 Arabidopsis thaliana 2.83 % 6.9e-05 0.000318
Cluster_97 Arabidopsis thaliana 2.41 % 0.001801 0.028704
Sequences (1227) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms