GO:0043765: T/G mismatch-specific endonuclease activity (Molecular function)

"Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine." [PMID:17651368]

There are 46 sequences with this label.

Enriched clusters

Name	Species	% in cluster	p-value	corrected p-value	action
Cluster_87	Arabidopsis thaliana	2.0 %	0.003613	0.024906

Sequences (46) (download table)

InterPro Domains

GO Terms

Family Terms

GO:0043765: T/G mismatch-specific endonuclease activity (Molecular function)

Associations