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GO:0017171: serine hydrolase activity (Molecular function)

"Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [Wikipedia:Serine_hydrolase]


There are 35887 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_95 Abrodictyum obscurum 2.8 % 0.000553 0.005667
Cluster_156 Abrodictyum obscurum 1.57 % 0.013827 0.039343
Cluster_98 Actinostachys digitata 2.66 % 6.8e-05 0.000846
Cluster_593 Actinostachys digitata 50.0 % 0.004417 0.019876
Cluster_232 Actinostachys digitata 4.29 % 0.000525 0.020669
Cluster_172 Actinostachys digitata 3.7 % 0.000803 0.011043
Cluster_95 Angiopteris evecta 1.38 % 0.019262 0.042621
Cluster_96 Adiantum latifolium 3.9 % 0.001116 0.029474
Cluster_112 Adiantum latifolium 4.69 % 0.000652 0.02705
Cluster_87 Adiantum latifolium 7.14 % 1.5e-05 0.000538
Cluster_132 Alsophila latebrosa 5.43 % 1e-06 8.1e-05
Cluster_208 Alsophila latebrosa 2.53 % 0.011637 0.045654
Cluster_525 Alsophila latebrosa 50.0 % 0.004104 0.013681
Cluster_408 Amblovenatum opulentum 33.33 % 0.007159 0.014007
Cluster_148 Amblovenatum opulentum 4.35 % 7.5e-05 0.000893
Cluster_126 Alsophila spinulosa 3.75 % 0.0007 0.033129
Cluster_28 Amborella trichopoda 7.48 % 0.0 3e-06
Cluster_74 Amborella trichopoda 11.11 % 0.0 0.0
Cluster_206 Cibotium barometz 2.22 % 0.00142 0.026851
Cluster_77 Chlamydomonas reinhardtii 4.55 % 0.013047 0.021058
Cluster_274 Diplazium proliferum (Lam.) Kaulf. 50.0 % 0.005028 0.016759
Cluster_146 Diplazium proliferum (Lam.) Kaulf. 10.42 % 0.0 6e-06
Cluster_68 Dicranopteris curranii 4.08 % 0.008019 0.040094
Cluster_516 Dicranopteris curranii 50.0 % 0.005459 0.024564
Cluster_414 Dicranopteris curranii 50.0 % 0.005459 0.031387
Cluster_110 Dicranopteris curranii 6.59 % 0.0 5e-06
Cluster_101 Dicranopteris curranii 3.6 % 0.000255 0.006495
Cluster_105 Dicranopteris curranii 2.96 % 0.000536 0.019518
Cluster_77 Dicranopteris curranii 1.75 % 0.011718 0.030183
Cluster_124 Davallia denticulata 4.26 % 0.003515 0.042185
Cluster_100 Ginkgo biloba 8.47 % 1e-06 8e-06
Cluster_327 Ginkgo biloba 100.0 % 9e-06 5.3e-05
Cluster_154 Ginkgo biloba 4.65 % 0.007332 0.049033
Cluster_369 Ginkgo biloba 50.0 % 0.005946 0.032705
Cluster_80 Ginkgo biloba 4.88 % 0.006684 0.024679
Cluster_107 Ginkgo biloba 5.66 % 0.000541 0.022734
Cluster_131 Lindsaea ensifolia 1.72 % 0.005742 0.021819
Cluster_55 Lindsaea ensifolia 1.6 % 0.007102 0.040049
Cluster_98 Lindsaea ensifolia 1.59 % 0.007206 0.028632
Cluster_161 Lygodium flexuosum 3.92 % 0.005585 0.009648
Cluster_47 Lygodium flexuosum 2.4 % 0.002624 0.020172
Cluster_30 Lygodium flexuosum 3.64 % 0.006469 0.044473
Cluster_83 Lygodium flexuosum 1.52 % 0.009263 0.047911
Cluster_96 Microlepia speluncae 3.12 % 0.005991 0.025463
Cluster_17 Microlepia speluncae 2.19 % 0.000345 0.005174
Cluster_8 Marchantia polymorpha 3.77 % 0.00955 0.034752
Cluster_139 Marchantia polymorpha 50.0 % 0.005553 0.034709
Cluster_30 Marchantia polymorpha 2.61 % 0.004028 0.017238
Cluster_138 Nephrolepis biserrata 2.61 % 0.002922 0.020451
Cluster_99 Nephrolepis biserrata 1.82 % 0.007962 0.032195
Cluster_289 Nephrolepis biserrata 2.13 % 0.005168 0.020671
Cluster_60 Ophioglossum reticulatum 4.76 % 6e-06 0.000402
Cluster_145 Ophioglossum reticulatum 8.89 % 5e-06 0.000224
Cluster_121 Ophioglossum reticulatum 4.49 % 6.9e-05 0.000256
Cluster_43 Ophioglossum reticulatum 1.61 % 0.010713 0.043825
Cluster_68 Oryza sativa 8.16 % 3.7e-05 0.001417
Cluster_48 Oryza sativa 3.45 % 0.001026 0.006092
Cluster_330 Oryza sativa 50.0 % 0.007571 0.02163
Cluster_135 Oryza sativa 6.82 % 0.000632 0.00496
Cluster_346 Oryza sativa 50.0 % 0.007571 0.034068
Cluster_81 Oryza sativa 5.45 % 4e-06 0.000268
Cluster_84 Oryza sativa 5.48 % 0.000177 0.001747
Cluster_669 Picea abies 50.0 % 0.006862 0.030878
Cluster_422 Picea abies 28.57 % 0.000244 0.002767
Cluster_253 Picea abies 11.36 % 0.0 1.2e-05
Cluster_609 Picea abies 50.0 % 0.006862 0.016773
Cluster_340 Picea abies 100.0 % 1.2e-05 5.3e-05
Cluster_546 Picea abies 100.0 % 1.2e-05 3.9e-05
Cluster_246 Picea abies 4.26 % 0.011483 0.03768
Cluster_136 Picea abies 10.17 % 0.0 2e-06
Cluster_39 Picea abies 3.17 % 0.020016 0.047585
Cluster_349 Pleocnemia irregularis 50.0 % 0.006401 0.019202
Cluster_426 Pleocnemia irregularis 50.0 % 0.006401 0.026184
Cluster_96 Psilotum nudum 3.03 % 0.00072 0.013415
Cluster_156 Pyrrosia piloselloides 2.38 % 0.014531 0.044502
Cluster_361 Pyrrosia piloselloides 50.0 % 0.004339 0.019524
Cluster_209 Salvinia molesta 25.0 % 0.013995 0.018806
Cluster_60 Salvinia molesta 10.14 % 0.0 0.0
Cluster_28 Salvinia molesta 3.7 % 0.000597 0.004072
Cluster_50 Salvinia molesta 5.32 % 2.2e-05 0.000503
Cluster_81 Salvinia molesta 2.62 % 0.000605 0.005711
Cluster_46 Salvinia molesta 11.8 % 0.0 0.0
Cluster_93 Salvinia molesta 5.6 % 0.0 2e-06
Cluster_115 Solanum lycopersicum 12.24 % 0.0 4e-06
Cluster_113 Solanum lycopersicum 8.33 % 0.000142 0.001143
Cluster_358 Solanum lycopersicum 50.0 % 0.010946 0.043783
Cluster_218 Selaginella moellendorffii 50.0 % 0.001884 0.005651
Cluster_20 Stenochlaena palustris 3.75 % 0.001122 0.023744
Cluster_95 Stenochlaena palustris 2.02 % 0.001655 0.006805
Cluster_36 Stenochlaena palustris 2.48 % 0.003647 0.041737
Cluster_130 Stenochlaena palustris 3.85 % 0.007721 0.028012
Cluster_2 Tectaria incisa 1.52 % 0.009174 0.023001
Cluster_15 Tectaria incisa 1.63 % 0.007619 0.034535
Cluster_47 Tectaria incisa 4.71 % 3.7e-05 0.001642
Cluster_44 Tectaria incisa 2.24 % 0.003162 0.01125
Cluster_72 Tectaria incisa 3.57 % 0.006648 0.015029
Cluster_118 Tectaria incisa 3.23 % 0.001116 0.035702
Cluster_20 Vitis vinifera 4.51 % 0.000332 0.004753
Cluster_301 Vitis vinifera 100.0 % 4.7e-05 0.000158
Cluster_350 Vitis vinifera 50.0 % 0.013769 0.034422
Cluster_53 Vitis vinifera 9.43 % 3.3e-05 0.000477
Cluster_123 Zea mays 5.88 % 7.6e-05 0.002446
Cluster_51 Zea mays 2.88 % 0.0049 0.02772
Cluster_105 Zea mays 2.04 % 0.004025 0.01776
Cluster_141 Arabidopsis thaliana 3.52 % 0.000903 0.014632
Sequences (35887) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !