GO:0016840: carbon-nitrogen lyase activity (Molecular function)

"Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99)." [EC:4.3.-.-]


There are 165 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_132 Arabidopsis thaliana 3.33 % 0.00106 0.008107
Cluster_45 Arabidopsis thaliana 1.9 % 0.0032 0.038351
Cluster_99 Arabidopsis thaliana 3.51 % 0.000957 0.024996
Cluster_122 Cyanophora paradoxa 1.45 % 0.011127 0.045992
Cluster_71 Chlamydomonas reinhardtii 1.06 % 0.021028 0.04556
Cluster_493 Oryza sativa 20.0 % 0.003 0.022999
Cluster_69 Oryza sativa 2.86 % 0.000815 0.007059
Cluster_46 Oryza sativa 1.87 % 0.001887 0.022391
Cluster_803 Picea abies 50.0 % 0.000759 0.002276
Cluster_149 Picea abies 1.1 % 0.002166 0.021757
Cluster_163 Solanum lycopersicum 2.0 % 0.000951 0.026636
Cluster_35 Solanum lycopersicum 0.95 % 0.004095 0.037383
Cluster_402 Vitis vinifera 50.0 % 0.002276 0.008346
Cluster_36 Vitis vinifera 2.6 % 0.0 2.6e-05
Cluster_428 Vitis vinifera 50.0 % 0.002276 0.006828
Cluster_459 Zea mays 20.0 % 0.004607 0.031482
Cluster_104 Zea mays 5.88 % 1.5e-05 0.000564
Cluster_709 Zea mays 50.0 % 0.001845 0.005536
Sequences (165) (download table)

InterPro Domains

GO Terms

Family Terms