GO:0016829: lyase activity (Molecular function)

"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [EC:4.-.-.-, ISBN:0198547684]


There are 1783 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_164 Arabidopsis thaliana 3.5 % 0.015124 0.027169
Cluster_132 Arabidopsis thaliana 10.0 % 3.2e-05 0.000317
Cluster_179 Arabidopsis thaliana 6.45 % 0.003562 0.010911
Cluster_45 Arabidopsis thaliana 6.67 % 9.6e-05 0.003299
Cluster_36 Arabidopsis thaliana 11.11 % 3e-06 1.9e-05
Cluster_264 Arabidopsis thaliana 4.71 % 0.010806 0.042803
Cluster_101 Cyanophora paradoxa 4.24 % 9.2e-05 0.003286
Cluster_44 Cyanophora paradoxa 5.08 % 0.00011 0.002331
Cluster_122 Cyanophora paradoxa 7.25 % 7.9e-05 0.001465
Cluster_200 Cyanophora paradoxa 6.52 % 0.00313 0.02973
Cluster_20 Cyanophora paradoxa 2.44 % 0.020852 0.042828
Cluster_21 Cyanophora paradoxa 3.59 % 0.000711 0.006479
Cluster_71 Cyanophora paradoxa 3.66 % 0.015469 0.029675
Cluster_146 Cyanophora paradoxa 5.52 % 1e-06 1.9e-05
Cluster_56 Chlamydomonas reinhardtii 12.31 % 0.0 1e-06
Cluster_112 Chlamydomonas reinhardtii 6.93 % 4.5e-05 0.000238
Cluster_11 Chlamydomonas reinhardtii 5.0 % 0.000133 0.000667
Cluster_197 Chlamydomonas reinhardtii 50.0 % 0.018627 0.032079
Cluster_9 Chlamydomonas reinhardtii 3.87 % 0.003404 0.029153
Cluster_108 Chlamydomonas reinhardtii 6.78 % 0.002255 0.029061
Cluster_78 Chlamydomonas reinhardtii 6.67 % 0.002398 0.043971
Cluster_59 Chlamydomonas reinhardtii 9.79 % 0.0 0.0
Cluster_155 Chlamydomonas reinhardtii 10.64 % 7.5e-05 0.000495
Cluster_34 Chlamydomonas reinhardtii 6.45 % 0.002704 0.026323
Cluster_23 Chlamydomonas reinhardtii 7.46 % 0.000408 0.031441
Cluster_294 Oryza sativa 5.45 % 0.002081 0.024121
Cluster_241 Oryza sativa 3.85 % 0.023814 0.039821
Cluster_77 Oryza sativa 3.33 % 0.00066 0.006325
Cluster_5 Oryza sativa 1.96 % 0.006573 0.03
Cluster_21 Oryza sativa 3.09 % 0.01017 0.02221
Cluster_157 Oryza sativa 3.8 % 0.005791 0.028064
Cluster_4 Oryza sativa 3.7 % 0.000108 0.004593
Cluster_491 Picea abies 13.04 % 0.0 2e-06
Cluster_840 Picea abies 100.0 % 2.2e-05 6.1e-05
Cluster_1250 Picea abies 50.0 % 0.009422 0.0197
Cluster_1093 Picea abies 50.0 % 0.009422 0.028265
Cluster_803 Picea abies 50.0 % 0.009422 0.021198
Cluster_827 Picea abies 50.0 % 0.009422 0.014132
Cluster_270 Picea abies 2.74 % 0.005245 0.037634
Cluster_217 Picea abies 8.33 % 1e-05 0.000131
Cluster_670 Picea abies 100.0 % 2.2e-05 6.1e-05
Cluster_1297 Picea abies 50.0 % 0.009422 0.018843
Cluster_296 Picea abies 4.96 % 2.6e-05 0.000865
Cluster_357 Picea abies 6.25 % 0.001542 0.004211
Cluster_325 Picea abies 5.88 % 0.0 3e-06
Cluster_149 Picea abies 4.42 % 3e-06 0.000121
Cluster_436 Picea abies 5.45 % 0.002283 0.028151
Cluster_327 Picea abies 4.96 % 2.6e-05 0.000385
Cluster_197 Picea abies 7.69 % 2e-06 7.3e-05
Cluster_940 Picea abies 50.0 % 0.009422 0.028265
Cluster_1160 Picea abies 33.33 % 0.014099 0.021149
Cluster_1202 Picea abies 33.33 % 0.014099 0.038773
Cluster_11 Selaginella moellendorfii 2.2 % 0.001213 0.016626
Cluster_38 Selaginella moellendorfii 3.09 % 0.001973 0.028409
Cluster_51 Solanum lycopersicum 3.36 % 0.001142 0.025321
Cluster_9 Solanum lycopersicum 3.23 % 0.001361 0.028803
Cluster_210 Solanum lycopersicum 2.74 % 0.007334 0.029444
Cluster_56 Solanum lycopersicum 4.44 % 0.001292 0.025034
Cluster_457 Solanum lycopersicum 50.0 % 0.010409 0.019593
Cluster_170 Solanum lycopersicum 6.12 % 0.002158 0.030432
Cluster_46 Solanum lycopersicum 9.65 % 0.0 0.0
Cluster_402 Vitis vinifera 50.0 % 0.016406 0.045115
Cluster_218 Vitis vinifera 6.15 % 0.002046 0.021952
Cluster_66 Vitis vinifera 6.06 % 0.002164 0.023268
Cluster_62 Vitis vinifera 6.59 % 0.000108 0.004164
Cluster_36 Vitis vinifera 3.03 % 0.00314 0.048275
Cluster_428 Vitis vinifera 50.0 % 0.016406 0.036913
Cluster_418 Vitis vinifera 50.0 % 0.016406 0.036092
Cluster_98 Vitis vinifera 5.45 % 0.010556 0.030465
Cluster_78 Vitis vinifera 16.25 % 0.0 0.0
Cluster_442 Zea mays 50.0 % 0.010689 0.046321
Cluster_169 Zea mays 5.71 % 0.000557 0.020059
Cluster_459 Zea mays 20.0 % 0.026511 0.044365
Cluster_156 Zea mays 3.85 % 0.008593 0.020754
Cluster_726 Zea mays 33.33 % 0.015991 0.023987
Cluster_69 Zea mays 3.49 % 1.2e-05 7.4e-05
Cluster_104 Zea mays 5.88 % 0.002614 0.030325
Cluster_709 Zea mays 50.0 % 0.010689 0.024051
Cluster_502 Zea mays 50.0 % 0.010689 0.046321
Cluster_46 Zea mays 3.43 % 0.00038 0.001397
Cluster_319 Zea mays 7.41 % 0.000205 0.005013
Cluster_410 Zea mays 50.0 % 0.010689 0.033137
Cluster_12 Zea mays 4.23 % 0.0 1.5e-05
Sequences (1783) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms