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GO:0016840: carbon-nitrogen lyase activity (Molecular function)

"Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99)." [EC:4.3.-.-]


There are 171 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_47 Amborella trichopoda 1.23 % 0.003036 0.041571
Cluster_14 Arabidopsis thaliana 1.44 % 0.005424 0.040021
Cluster_141 Arabidopsis thaliana 2.6 % 0.001705 0.009787
Cluster_155 Arabidopsis thaliana 2.25 % 0.002269 0.034265
Cluster_66 Chlamydomonas reinhardtii 1.75 % 0.012791 0.020403
Cluster_194 Gingko biloba 1.47 % 0.021193 0.048979
Cluster_169 Oryza sativa 2.5 % 0.000954 0.014963
Cluster_46 Oryza sativa 3.23 % 0.000574 0.006462
Cluster_13 Oryza sativa 0.87 % 0.007484 0.039333
Cluster_145 Physcomitrella patens 1.59 % 0.005812 0.039714
Cluster_30 Picea abies 1.33 % 4.2e-05 0.000289
Cluster_88 Selaginella moellendorffii 1.05 % 0.008508 0.047205
Cluster_55 Vitis vinifera 6.58 % 0.0 1e-06
Cluster_396 Vitis vinifera 50.0 % 0.002276 0.008346
Cluster_422 Vitis vinifera 50.0 % 0.002276 0.006828
Cluster_76 Zea mays 1.9 % 0.000484 0.004204
Cluster_20 Zea mays 1.72 % 0.017987 0.028651
Cluster_206 Zea mays 1.59 % 0.000695 0.019933
Cluster_162 Zea mays 1.27 % 0.024426 0.048096
Cluster_42 Zea mays 3.08 % 0.000186 0.006993
Sequences (171) (download table)

InterPro Domains

GO Terms

Family Terms