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GO:0016829: lyase activity (Molecular function)

"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [ISBN:0198547684]


There are 35749 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_12 Abrodictyum obscurum 3.14 % 0.000297 0.005426
Cluster_263 Abrodictyum obscurum 50.0 % 0.009343 0.016817
Cluster_184 Abrodictyum obscurum 7.14 % 0.001015 0.014073
Cluster_207 Abrodictyum obscurum 50.0 % 0.009343 0.018018
Cluster_24 Abrodictyum obscurum 2.72 % 0.001811 0.024594
Cluster_198 Actinostachys digitata 5.69 % 3e-06 0.000382
Cluster_45 Actinostachys digitata 4.21 % 6e-06 0.001767
Cluster_19 Actinostachys digitata 2.94 % 0.014443 0.044168
Cluster_571 Actinostachys digitata 50.0 % 0.009878 0.020305
Cluster_229 Actinostachys digitata 6.15 % 0.0 7.6e-05
Cluster_326 Actinostachys digitata 6.0 % 0.001992 0.006197
Cluster_590 Actinostachys digitata 50.0 % 0.009878 0.027165
Cluster_56 Actinostachys digitata 3.07 % 0.001389 0.02011
Cluster_66 Actinostachys digitata 2.65 % 0.002646 0.036789
Cluster_372 Actinostachys digitata 7.14 % 0.001201 0.006099
Cluster_96 Angiopteris evecta 2.29 % 0.001281 0.011189
Cluster_237 Angiopteris evecta 50.0 % 0.005324 0.011028
Cluster_95 Angiopteris evecta 2.07 % 0.006995 0.023216
Cluster_172 Angiopteris evecta 33.33 % 0.007975 0.017827
Cluster_109 Azolla filiculoides 5.15 % 0.003907 0.044425
Cluster_9 Adiantum latifolium 2.17 % 0.013085 0.047044
Cluster_21 Adiantum latifolium 3.39 % 0.018601 0.044305
Cluster_24 Adiantum latifolium 2.84 % 0.001621 0.005512
Cluster_158 Adiantum latifolium 33.33 % 0.010565 0.025479
Cluster_39 Adiantum latifolium 2.91 % 0.000378 0.002562
Cluster_212 Alsophila latebrosa 4.88 % 0.011359 0.036511
Cluster_140 Alsophila latebrosa 2.52 % 0.003683 0.015456
Cluster_37 Alsophila latebrosa 3.55 % 0.00025 0.021144
Cluster_228 Alsophila latebrosa 7.06 % 1e-06 5.6e-05
Cluster_129 Alsophila latebrosa 4.82 % 0.000333 0.007323
Cluster_327 Alsophila latebrosa 50.0 % 0.007828 0.017614
Cluster_271 Amblovenatum opulentum 3.65 % 0.000155 0.003337
Cluster_6 Alsophila spinulosa 2.34 % 0.003004 0.017289
Cluster_32 Alsophila spinulosa 2.79 % 0.000412 0.022616
Cluster_202 Amborella trichopoda 50.0 % 0.012191 0.033091
Cluster_234 Amborella trichopoda 50.0 % 0.012191 0.024383
Cluster_188 Amborella trichopoda 50.0 % 0.012191 0.025254
Cluster_45 Amborella trichopoda 8.06 % 3.9e-05 0.000989
Cluster_15 Amborella trichopoda 11.39 % 0.0 0.0
Cluster_59 Cibotium barometz 4.52 % 2e-06 9.4e-05
Cluster_119 Cibotium barometz 4.08 % 0.014246 0.043113
Cluster_64 Cibotium barometz 8.7 % 2.6e-05 0.000827
Cluster_37 Cibotium barometz 1.96 % 0.019414 0.037086
Cluster_350 Cibotium barometz 25.0 % 0.014684 0.039416
Cluster_95 Cibotium barometz 3.48 % 0.000912 0.031677
Cluster_288 Cibotium barometz 3.85 % 0.00013 0.002333
Cluster_480 Cibotium barometz 50.0 % 0.007369 0.022458
Cluster_72 Cibotium barometz 6.67 % 0.00063 0.002519
Cluster_21 Cyanophora paradoxa 3.81 % 0.004566 0.038814
Cluster_8 Chlamydomonas reinhardtii 5.26 % 0.016799 0.042874
Cluster_77 Chlamydomonas reinhardtii 13.64 % 3e-06 2.3e-05
Cluster_116 Chlamydomonas reinhardtii 50.0 % 0.01885 0.034374
Cluster_25 Chlamydomonas reinhardtii 6.0 % 0.011805 0.021286
Cluster_68 Chlamydomonas reinhardtii 7.69 % 0.001474 0.040176
Cluster_44 Chlamydomonas reinhardtii 8.82 % 4.4e-05 0.000121
Cluster_79 Chlamydomonas reinhardtii 6.58 % 0.000771 0.002279
Cluster_14 Chlamydomonas reinhardtii 6.38 % 0.009969 0.026319
Cluster_3 Chlamydomonas reinhardtii 9.8 % 0.000119 0.00028
Cluster_442 Ceratopteris richardii 33.33 % 0.015789 0.047366
Cluster_13 Ceratopteris richardii 4.55 % 0.001253 0.010242
Cluster_404 Ceratopteris richardii 50.0 % 0.010554 0.026384
Cluster_73 Diplazium proliferum (Lam.) Kaulf. 2.11 % 0.00269 0.023464
Cluster_119 Diplazium proliferum (Lam.) Kaulf. 4.3 % 0.000187 0.008132
Cluster_44 Diplazium proliferum (Lam.) Kaulf. 6.45 % 3.8e-05 0.001286
Cluster_59 Dicranopteris curranii 2.63 % 0.001804 0.015176
Cluster_492 Dicranopteris curranii 16.67 % 0.020041 0.045091
Cluster_41 Dicranopteris curranii 4.26 % 0.01104 0.029355
Cluster_202 Dicranopteris curranii 4.0 % 0.012428 0.03107
Cluster_483 Dicranopteris curranii 50.0 % 0.006725 0.01345
Cluster_73 Davallia denticulata 1.9 % 0.017003 0.04503
Cluster_367 Davallia denticulata 50.0 % 0.006793 0.043307
Cluster_93 Davallia denticulata 3.51 % 0.016253 0.037923
Cluster_53 Equisetum hyemale 3.1 % 0.000674 0.018023
Cluster_106 Ginkgo biloba 6.33 % 4.1e-05 0.001294
Cluster_414 Ginkgo biloba 50.0 % 0.009563 0.021039
Cluster_184 Ginkgo biloba 50.0 % 0.009563 0.021735
Cluster_424 Ginkgo biloba 33.33 % 0.014311 0.038414
Cluster_71 Ginkgo biloba 5.19 % 0.000527 0.007757
Cluster_99 Lindsaea ensifolia 3.64 % 0.012732 0.037797
Cluster_233 Lindsaea ensifolia 33.33 % 0.009267 0.014415
Cluster_194 Lindsaea ensifolia 50.0 % 0.006187 0.015984
Cluster_48 Lindsaea ensifolia 2.04 % 0.010955 0.033741
Cluster_56 Lindsaea ensifolia 3.5 % 8.9e-05 0.000971
Cluster_236 Lindsaea ensifolia 20.0 % 0.015397 0.044266
Cluster_43 Lindsaea ensifolia 3.41 % 2e-05 0.000103
Cluster_212 Lygodium flexuosum 50.0 % 0.007443 0.012405
Cluster_38 Lygodium flexuosum 5.0 % 3.8e-05 0.001414
Cluster_74 Microlepia speluncae 2.21 % 0.00147 0.005482
Cluster_17 Microlepia speluncae 1.64 % 0.013265 0.047689
Cluster_56 Microlepia speluncae 4.76 % 0.000661 0.004497
Cluster_220 Marchantia polymorpha 50.0 % 0.009555 0.024417
Cluster_11 Marchantia polymorpha 3.03 % 0.00038 0.029459
Cluster_46 Marchantia polymorpha 3.29 % 0.000822 0.015244
Cluster_32 Marchantia polymorpha 2.94 % 0.004152 0.013691
Cluster_66 Marchantia polymorpha 2.73 % 0.015869 0.039768
Cluster_12 Nephrolepis biserrata 1.78 % 0.009358 0.041904
Cluster_240 Nephrolepis biserrata 33.33 % 0.00762 0.024766
Cluster_202 Nephrolepis biserrata 100.0 % 6e-06 0.000156
Cluster_165 Nephrolepis biserrata 3.31 % 0.000269 0.003514
Cluster_244 Nephrolepis biserrata 2.33 % 0.020445 0.041138
Cluster_243 Nephrolepis biserrata 50.0 % 0.005087 0.010173
Cluster_91 Ophioglossum reticulatum 1.92 % 0.014204 0.047939
Cluster_13 Oryza sativa 2.42 % 0.007793 0.035968
Cluster_28 Oryza sativa 3.01 % 0.00366 0.026704
Cluster_154 Oryza sativa 8.89 % 6e-05 0.000697
Cluster_183 Oryza sativa 4.65 % 0.017442 0.041228
Cluster_298 Oryza sativa 33.33 % 0.014014 0.036036
Cluster_84 Oryza sativa 4.11 % 0.004975 0.030233
Cluster_67 Picea abies 7.69 % 9e-05 0.000483
Cluster_1041 Picea abies 50.0 % 0.008925 0.019634
Cluster_192 Picea abies 5.56 % 0.000318 0.002826
Cluster_1022 Picea abies 50.0 % 0.008925 0.013387
Cluster_100 Picea abies 2.52 % 0.005845 0.015654
Cluster_28 Picea abies 15.38 % 0.0 0.0
Cluster_151 Picea abies 4.35 % 0.018127 0.04475
Cluster_159 Picea abies 5.17 % 0.002278 0.009989
Cluster_652 Picea abies 50.0 % 0.008925 0.013387
Cluster_63 Picea abies 10.24 % 0.0 0.0
Cluster_35 Picea abies 10.87 % 2e-06 1.3e-05
Cluster_156 Picea abies 5.56 % 0.001856 0.005498
Cluster_739 Picea abies 50.0 % 0.008925 0.020527
Cluster_229 Picea abies 10.2 % 3e-06 0.00034
Cluster_188 Picea abies 7.14 % 0.000893 0.008514
Cluster_86 Picea abies 4.0 % 0.021205 0.041447
Cluster_150 Picea abies 3.23 % 0.008544 0.030018
Cluster_104 Picea abies 5.36 % 0.00206 0.009843
Cluster_243 Picea abies 6.38 % 0.001241 0.023275
Cluster_131 Picea abies 4.55 % 0.003291 0.016637
Cluster_289 Picea abies 50.0 % 0.008925 0.023799
Cluster_575 Picea abies 33.33 % 0.013357 0.031167
Cluster_332 Picea abies 50.0 % 0.008925 0.034211
Cluster_114 Picea abies 5.0 % 9.2e-05 0.002301
Cluster_1072 Picea abies 50.0 % 0.008925 0.026774
Cluster_212 Pleocnemia irregularis 4.69 % 0.002295 0.015008
Cluster_445 Pleocnemia irregularis 50.0 % 0.008102 0.032408
Cluster_373 Pleocnemia irregularis 50.0 % 0.008102 0.018004
Cluster_54 Pleocnemia irregularis 5.56 % 6e-06 0.000295
Cluster_226 Pleocnemia irregularis 2.37 % 0.005161 0.040334
Cluster_162 Pleocnemia irregularis 5.0 % 0.001908 0.039112
Cluster_358 Pleocnemia irregularis 33.33 % 0.012128 0.030321
Cluster_500 Pleocnemia irregularis 50.0 % 0.008102 0.016204
Cluster_135 Psilotum nudum 4.55 % 0.008163 0.036199
Cluster_82 Physcomitrella patens 2.47 % 0.002729 0.011356
Cluster_59 Pyrrosia piloselloides 3.43 % 0.00017 0.021197
Cluster_443 Pyrrosia piloselloides 50.0 % 0.009162 0.018324
Cluster_82 Pyrrosia piloselloides 4.12 % 0.001079 0.034315
Cluster_48 Pyrrosia piloselloides 4.76 % 0.003105 0.03001
Cluster_395 Pyrrosia piloselloides 50.0 % 0.009162 0.028795
Cluster_84 Pyrrosia piloselloides 4.71 % 0.0 7.1e-05
Cluster_132 Salvinia molesta 3.9 % 0.001304 0.013159
Cluster_126 Solanum lycopersicum 5.36 % 0.003807 0.014065
Cluster_98 Solanum lycopersicum 11.3 % 0.0 0.0
Cluster_142 Solanum lycopersicum 7.32 % 0.001556 0.019922
Cluster_8 Solanum lycopersicum 2.51 % 0.005295 0.032938
Cluster_400 Solanum lycopersicum 50.0 % 0.011121 0.024713
Cluster_409 Solanum lycopersicum 33.33 % 0.016635 0.034459
Cluster_212 Stenochlaena palustris 7.14 % 0.000225 0.001332
Cluster_41 Stenochlaena palustris 2.8 % 0.003402 0.024886
Cluster_226 Stenochlaena palustris 50.0 % 0.005561 0.011123
Cluster_70 Stenochlaena palustris 3.77 % 0.009675 0.03044
Cluster_2 Tectaria incisa 1.52 % 0.023526 0.044724
Cluster_132 Tectaria incisa 4.55 % 0.001149 0.042526
Cluster_78 Vitis vinifera 4.76 % 0.005421 0.033715
Cluster_296 Vitis vinifera 50.0 % 0.016631 0.037421
Cluster_37 Vitis vinifera 26.53 % 0.0 0.0
Cluster_41 Vitis vinifera 11.9 % 2.6e-05 0.000611
Cluster_270 Vitis vinifera 50.0 % 0.016631 0.045736
Cluster_286 Vitis vinifera 50.0 % 0.016631 0.036589
Cluster_84 Vitis vinifera 5.0 % 0.001536 0.022572
Cluster_398 Zea mays 25.0 % 0.0154 0.027949
Cluster_40 Zea mays 9.43 % 2e-06 8e-06
Cluster_414 Zea mays 33.33 % 0.011573 0.027003
Cluster_28 Zea mays 2.19 % 0.016373 0.044117
Cluster_649 Zea mays 50.0 % 0.00773 0.029632
Cluster_149 Zea mays 17.78 % 0.0 0.0
Cluster_717 Zea mays 50.0 % 0.00773 0.029816
Cluster_12 Arabidopsis thaliana 6.82 % 0.009631 0.034903
Cluster_38 Arabidopsis thaliana 10.64 % 0.000104 0.000947
Cluster_272 Arabidopsis thaliana 100.0 % 1e-06 3e-06
Cluster_117 Arabidopsis thaliana 4.35 % 0.013666 0.038001
Cluster_115 Arabidopsis thaliana 5.06 % 0.008122 0.027512
Cluster_114 Arabidopsis thaliana 4.95 % 0.003471 0.03978
Cluster_5 Arabidopsis thaliana 4.42 % 0.005587 0.015994
Sequences (35749) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !